We present for the first time a diode end-pumped acousto-optic (AO) Q-switched Nd:Y0.8Lu0.2VO4 crystal laser with a comparative planar-planar cavity in this paper. The maximum continuous wave (CW) power of 5.61 W is achieved at the incident pump power of 13.07 W with 20% transmission for the output coupler, resulting in an optical-to-optical conversion efficiency of 43%. For Q-switching operation, at the incident pump power of 13.07 W and 1 kHz repetition rate, the shortest pulse width of 11 ns is measured and the highest peak power of 225.45 kW is obtained for the output transmission of 50%. At 100 kHz repetition rate and 20% output transmission, the maximum average output power of 4.23 W is reached. Peak power versus the incident pump power for the Q-switched laser with different output couplers