A New Device and Technology for Detecting Bacterial Infection and its Gram Type in Diabetic Foot Ulcer

Parekh, Janakrai N.; Soni, Payal; Meena, Mamta; Tandel, Chetan; Radhakrishanan, Geethanjali

doi:10.1007/s12262-021-03190-6

Cited by 2 publications

(3 citation statements)

References 11 publications

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“…The excitation of porphyrins with blue light (excitation wavelength: 405 nm) results in the emission of red fluorescence. For example, the Pseudomonas aeruginosa bacterium produces a typical green/cyan fluorescence signal (emission wavelength: 460 nm) due to the presence of fluorescent siderophores, pyocyanin and pyoverdine [51]. The Gram-type of bacteria can also be distinguished with the characteristic autofluorescence emission; Gram-negative bacteria have a higher intensity of nicotinamide adenine dinucleotide (NADH) (emission wavelength: 470 nm) and flavin (emission wavelength: 525 nm) than gram-positive bacteria [52].…”

Section: Wound Infection Assessmentmentioning

confidence: 99%

Point‐of‐care optical devices in clinical imaging and screening: A review on the state of the art

Raj¹,

Khan²,

Shariq³

et al. 2023

Journal of Biophotonics

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Integration of optical technologies in biomedical sciences permitted light manipulation at smaller time-length scales for specific detection and imaging of biological entities. Similarly, advances in consumer electronics and wireless telecommunications strengthened the development of affordable and portable point-of-care (POC) optical devices, circumventing the necessity of conventional clinical analyses by trained personnel. However, many of the POC optical technologies translated from bench to bedside require industrial support for their commercialization and dissemination to the population. This review aims to demonstrate the intriguing progress and challenges of emerging POC devices utilizing optics for clinical imaging (depth-resolved and perfusion imaging) and screening (infections, cancer, cardiac health, and haematologic disorders) with a focus on research studies over the previous 3 years. Special attention is given to POC optical devices that can be utilized in resource-constrained environments.

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Section: Wound Infection Assessmentmentioning

confidence: 99%

Point‐of‐care optical devices in clinical imaging and screening: A review on the state of the art

Raj¹,

Khan²,

Shariq³

et al. 2023

Journal of Biophotonics

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“…Alat ini juga dapat mengukur dimensi ulkus, sehingga mengukut lama waktu penyembuhan luka. Laporan hasil dari pendokumentasian menggunakan alat tersebut dapat disimpan dan ditransfer baik menggunakan drive USB atau melalui cloud, terhubung dengan catatan rumah sakit (Parekh, Soni, Meena, Tandel, & Radhakrishanan, 2022). Kecanggihan alat ini mendorong peneliti untuk mengevaluasi akurasi dari FL-Imaging Device dan membandingkannya dengan standar emas yang digunakan saat ini.…”

Section: Pendahuluanunclassified

“…Dari 149 luka, FL-Imaging Device mendeteksi bakteri pada 89,9% (134/149) luka, hal tersebut dibandingkan dengan hasil kultur luka yang dilakukan di dalam lab, dan hasilnya adalah dari 149 luka diketahui bahwa hanya 88,5% (132/149) luka yang terdeteksi adanya bakteri. Sehingga dalam penelitiannya disimpulkan bahwa FL-Imaging Device memiliki keakuratan sebesar 99,24% (Parekh, Soni, Meena, Tandel, & Radhakrishanan, 2022). Pada 203 luka, FL-Imaging Device dapat mendeteksi bakteri pada 71,92% (146/203) luka, dan hal tersebut dibandingkan dengan hasil kultur yang telah dilakukan yaitu terdapat bakteri pada 86,2% (175/203) luka.…”

Section: Pembahasan Akurasi Dalam Mendeteksi Bakteri Dan Pengukuran Lukaunclassified

Penggunaan perangkat pencitraan fluoresensi bakteri pada luka: A literature review

Firstayude,

Rahman

2023

J.HolHealth

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Background: The incidence of chronic infections in wounds of DFU patients is caused by several factors, one of which is the slow diagnosis of diagnosis. The gold standard currently used to identify bacterial infections in wounds is the culture method which takes 2-3 days. FL-Imaging Device is a new technology for detecting bacteria in wounds in a matter of minutes.Purpose: To determine the effectiveness of using the Bacterial Fluorescence Imaging Device in identifying infectious bacteria in diabetic foot wounds.Method: The design of this research is a literature review study with reference sources for articles from journals that have been indexed and can be accessed via Sciencedirect, SCOPUS, Clinical Key and EBSCO which were published in the last 5 years (2018-2023). Inclusion criteria are articles that can be accessed in full text, in Indonesian or English and in accordance with the research topic.Results: Based on the 10 articles reviewed, it is known that the FL-Imanging Device is effective and accurate in detecting infectious bacteria in diabetic foot wounds. It is also known that using the FL-Imanging Device can change treatment plans, reduce the use of AMD, reduce the use of antibiotics, reduce treatment costs and speed up wound healing.Conclusion: The FL-Imaging Device can help identify the bacterial burden early, monitor the extent to which treatment is effective during and after debridement (wound cleaning), and support reducing antibiotic prescriptions and the use of AMD. With this, it is hoped that it can improve wound healing results. Keywords: Bacterial Fluorescence Imaging Device; Infection; Wound. Pendahuluan: Kejadian infeksi kronis pada luka pasien DFU diakibatkan oleh beberapa faktor, salah satunya adalah lambatnya penegakkan diganosa. Standar emas yang saat ini digunakan dalam mengidentifikasi bakteri infeksi pada luka adalah metode kultur yang memakan waktu 2-3 hari. FL-Imaging Device merupakan tekhnologi baru untuk mendeteksi bakteri pada luka dalam hitungan menit.Tujuan: Untuk mengetahui efektivitas penggunaaan Bacterial Fluorescence Imaging Device dalam mengidentifikasi bakteri infeksi pada luka kaki diabetik.Metode: Desain penelitian ini adalah studi literature review denan sumber referensi artikel dari jurnal yang telah terindeks dan dapat diakses melalui Sciencedirect, SCOPUS, Clinical Key dan EBSCO yang diterbitkan pada 5 tahun terakhir (2018-2023). Kriteria inklusi artikel yang dapat diaksses secara full text, berbahasa Indonesia atau Inggris dan sesuai dengan topik penelitian.Hasil: Berdasarkan 10 artikel yang ditelaah, diketahui bahwa FL-Imanging Device efektif serta akurat dalam mendektsi bakteri infeksi yang ada pada luka kaki diabetik. Diketahui juga, bahwa dengan menggunakan bahwa FL-Imanging Device dapat merubah rencana perawatan, mengurangi penggunaan AMD, pengurangi penggunaan antibiotic, mengurangi biata perawatan dan mempercepat penyembuhan luka.Simpulan: FL-Imaging Device dapat membantu dalam mengidentifikasi beban bakteri secara dini, memantau sejauh mana pengobatan efektif selama dan setelah debridemen (pembersihan luka), serta mendukung untuk mengurangi resep antibiotik dan penggunaan AMD. Dengan tersebut, diharapkan dapat meningkatkan hasil penyembuhan luka.

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A New Device and Technology for Detecting Bacterial Infection and its Gram Type in Diabetic Foot Ulcer

Cited by 2 publications

References 11 publications

Point‐of‐care optical devices in clinical imaging and screening: A review on the state of the art

Point‐of‐care optical devices in clinical imaging and screening: A review on the state of the art

Penggunaan perangkat pencitraan fluoresensi bakteri pada luka: A literature review

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