A new di-μ-oxo bis[oxovanadium(V)] complex containing Schiff base ligand derived from 1,2-diaminopropane and 2′-hydroxy-4′-methoxyacetophenone: Synthesis, structure and catalytic properties

Rayati, Saeed; Sadeghzadeh, Nasrin; Khavasi, Hamid Reza

doi:10.1016/j.inoche.2007.09.023

Cited by 45 publications

(19 citation statements)

References 32 publications

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“…Their enduring appeal and increasing popularity can be explained by the ease with which they are synthesized, the outstanding versatility they have, and a great deal of complexing ability they show39. Moreover, Schiff base ligands may be tuned both sterically and electronically by the variation of respective amine and aldehyde or ketone ligand precursors 40…”

Section: Introductionmentioning

confidence: 99%

Synthesis, Characterization, and Catalytic Performance in Oxidation of Styrene and α‐Methyl Styrene of a Nickel(II) Complex Derived from a Schiff Base Ligand

Heshmatpour¹,

Rayati²,

Hajiabbas³

et al. 2011

Zeitschrift anorg allge chemie

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Section: Introductionmentioning

confidence: 99%

Synthesis, Characterization, and Catalytic Performance in Oxidation of Styrene and α‐Methyl Styrene of a Nickel(II) Complex Derived from a Schiff Base Ligand

Heshmatpour¹,

Rayati²,

Hajiabbas³

et al. 2011

Zeitschrift anorg allge chemie

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“…Each V atom in the complex is six coordinated through three bonds to oxo groups and through bonds to the tridentate Schiff base ligand L 2 , forming an octahedral geometry. The distance be [18][19][20]. The distortion of the octa hedral coordination can be observed by the coordinate bond angles ranging from 76.2(1)° to 106.6(1)° for the perpendicular angles and from 155.7(1)° to 173.2(1)°f or the diagonal angles.…”

Section: Resultsmentioning

confidence: 99%

Synthesis and crystal structures of the dioxovanadium complexes [VO2L1] and [VO2L2]2

Liu

2012

Russ J Coord Chem

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Two new oxovanadium complexes, [VO 2 L 1 ] (I) and [VO 2 L 2 ] 2 (II), where L 1 and L 2 are the depro tonated forms of 4 bromo 2 [(2 diethylaminoethylimino)methyl]phenol (HL 1 ) and 4 bromo 2 {[2 (2 hydroxyethylamino)ethylimino]methyl}phenol (HL 2 ), respectively, have been synthesized and characterized by IR spectra and single crystal X ray diffraction. The crystal of I is monoclinic: space group P2 1 /n, a = 14.300 (3), b = 7.010(2), c = 15.460(2) Å, β = 107.401(2)°, V = 1478.7(5) Å 3 , Z = 4. The crystal of II is mon oclinic: space group P2 1 /c, a = 7.270(2), b = 15.373(3), c = 11.893(3) Å, β = 99.302(2)°, V = 1311.8(5) Å 3 , Z = 2.Complex I is a mononuclear dioxovanadium(IV) complex. Complex II is a centrosymmetric dinuclear dioxovanadium(V) complex with a V⋅⋅⋅V distance of 3.117(2) Å. The V atom in I is in a distorted square pyra midal coordination, and that in II is in an octahedral coordination. The difference in the structures of the complexes is largely induced by the hydrogen bonds during the self assembly process.

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“…Most of the schiff base compounds and their complexes with transition metals have wide biological and pharmaceutical applications (Padhye & Kauffman, ; Salam et al, ; Wang, Zhu, Yang, Wu, & Wang, ). Thiosemicarbazones having ONS coordinating sites are important in coordination chemistry due to their strong bonding ability with transition metals (Alomar, Khan, Allain, & Bouet, ; Rayati, Sadeghzadeh, & Khavasi, ; Siddiki et al, ; Vieites et al, ). Researchers have focused on Pt(II) and Pd(II) complexes containing N and S donors due to metal based drugs exhibiting significant anticancer activity with lower toxicity and adverse effects (Faraglia et al, ; Salam, Affan, Arafat, Saha, & Nasrin, ).…”

Section: Introductionmentioning

confidence: 99%

“…Most of the schiff base compounds and their complexes with transition metals have wide biological and pharmaceutical applications (Padhye & Kauffman, 1985;Wang, Zhu, Yang, Wu, & Wang, 1991). Thiosemicarbazones having ONS coordinating sites are important in coordination chemistry due to their strong bonding ability with transition metals (Alomar, Khan, Allain, & Bouet, 2009;Rayati, Sadeghzadeh, & Khavasi, 2007;Siddiki et al, 2012;Vieites et al, 2009). Researchers have focused on Pt(II) and…”

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confidence: 99%

Schiff base‐nickel, palladium, and platinum complexes derived from N‐cyclohexyl hydrazine carbothioamide and 3‐hydroxy‐4‐methoxybenzaldehyde: Selective antiproliferative and proapoptotic effects against colorectal carcinoma

Arafath

Al‐Suede

Adam

et al. 2019

Drug Development Research

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The bidentate N‐cyclohexyl‐2‐(3‐hydroxy‐4‐methoxybenzylidene)hydrazine‐1‐carbothioamide Schiff base ligand (HL) was coordinated to divalent nickel, palladium and platinum ions to form square planar complexes. The nickel and palladium complexes, [NiL2], [PdL2] form square planar complexes with 2:1 ligand to metal ratio. The platinum complex, [PtL(dmso)Cl] formed a square planar complex with 1:1 ligand to metal ratio. Platinum undergoes in situ reaction with DMSO before complexing with the ligand in solution. The cytotoxicity of HL, [NiL2], [PdL2], and [PtL(dmso)Cl] were evaluated against human colon cancer cell line (HCT‐116), human cervical cancer (Hela) cell line, melanoma (B16F10) cells, and human normal endothelial cell lines (Eahy926) by MTT assay. The [NiL2] complex displayed selective cytotoxic effect against the HCT 116 cancer cell line with IC50 of 7.9 ± 0.2 μM. However, HL, [PdL2], and [PtL(dmso)Cl] only exhibited moderate cytotoxic activity with IC50 = 75.9 ± 2.4, 100.0 ± 1.8, and 101.0 ± 3.6 μM, respectively. The potent cytotoxicity of [NiL2] was characterized using Hoechst and Rhodamine assays. The nickel complex, [NiL2], caused remarkable nuclear condensation and reduction in mitochondrial membrane potential. In addition, molecular docking studies confirms that [NiL2] possesses significant binding efficiency with Tyrosine kinase. Altogether, the results revealed that [NiL2] exhibits cytotoxicity against the cancer cells via Tyrosine kinase‐induced proapoptosis pathway. This study demonstrates that the [NiL2] complex could be a promising therapeutic agent against colorectal carcinoma.

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A new di-μ-oxo bis[oxovanadium(V)] complex containing Schiff base ligand derived from 1,2-diaminopropane and 2′-hydroxy-4′-methoxyacetophenone: Synthesis, structure and catalytic properties

Cited by 45 publications

References 32 publications

Synthesis, Characterization, and Catalytic Performance in Oxidation of Styrene and α‐Methyl Styrene of a Nickel(II) Complex Derived from a Schiff Base Ligand

Synthesis, Characterization, and Catalytic Performance in Oxidation of Styrene and α‐Methyl Styrene of a Nickel(II) Complex Derived from a Schiff Base Ligand

Synthesis and crystal structures of the dioxovanadium complexes [VO2L1] and [VO2L2]2

Schiff base‐nickel, palladium, and platinum complexes derived from N‐cyclohexyl hydrazine carbothioamide and 3‐hydroxy‐4‐methoxybenzaldehyde: Selective antiproliferative and proapoptotic effects against colorectal carcinoma

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