A New Dicationic Ring [(Water)6–(Ammonium)2] Acts as a Building Block for a Supramolecular 3D Assembly of Decavanadate Clusters and 4-(N,N-dimethylamino)pyridinium Ions

Abstract

A new dicationic ring [(water) 6 -(ammonium) 2 ] was found as a building block for a 3D supramolecular assembly of the compound [(CH 3 ) 2 NC 5 H 4 NH] 4 (NH 4 ) 2 [V 10 O 28 ]Á8H 2 O, 1, where (CH 3 ) 2 NC 5 H 4 NH = 4-(N,N-(dimethylamino)pyridinium) (DMAP ? ). The title compound was synthesized and characterized by single crystal X-ray diffraction at 100 K, infrared spectroscopy and thermogravimetric analysis. Compound 1 crystallizes in space group P-1 in the triclinic system with cell parameters: a = 11.1296(4) Å , b = 11.4790(4) Å , c = 11.8691(4) Å , a = 109.631(1)°, b = 100.601(1)°, c = 92.909(1)°and R(F 2 ) = 0.021. The threedimensional supramolecular structure is driven by intermolecular hydrogen bonds OÁÁÁH-N and OÁÁÁH-O from decavanadate anion with NH 4 ? and [(CH 3 ) 2-NC 5 H 4 NH] ? cations, as well as those formed between water molecules and decavanadate ions. The embedded rings consist of two sets of water-water-waterammonium chains joint together in a twisted chair conformation, in which water-ammonium pairs are at the top and bottom sites. The ring is hydrogen bond stabilized and represents to our knowledge, the first example of building block with this composition for a supramolecular structure to be reported.

Oxo/dioxo-vanadium(V) complexes with Schiff base ligands derived from 4-amino-5-mercapto-3-phenyl-1,2,4-triazole

“…The final step corresponds to decomposition of triazole molecules at 350-800 °C of the ligand leading to the final residue at 800 °C as metal oxide. The results show good agreement with the formulae suggested from the analytical data [37,38]. The total decomposition process can be represented as:…”

Decavanadate Salts of Cytosine and Metformin: A Combined Experimental-Theoretical Study of Potential Metallodrugs Against Diabetes and Cancer

“…Because of its high anionic charge, decavanadate is mainly stabilized by counterions through electrostatic interactions and hydrogen bonds . In previous works, decavanadate has been combined with a variety of cations, including protons, alkali-metal ions, ammonium, alkylammonium, phosphonium, organic and organometallic cations (Chinea et al, 2000 ; Lee and Joo, 2003 ; Correia et al, 2004 ; Kojima et al, 2011 ; Bartošová et al, 2012 ; Kioseoglou et al, 2013 ; Mal et al, 2013 ; Sánchez-Lombardo et al, 2014 ; Crans, 2015 ; Sánchez-Lara et al, 2015 , 2016b ). In this work, we combined decavanadate with two biologically relevant molecules Cytosine and Metformin (Scheme 2 ) with the aim to synthesize compounds with potential pharmacological activity.…”

Pharmacological and Toxicological Threshold of Bisammonium Tetrakis 4-(N,N-Dimethylamino)pyridinium Decavanadate in a Rat Model of Metabolic Syndrome and Insulin Resistance

“…After obtaining an orange solution from this process, 0.122 g (1 mmol) of 4-dimethylaminopyridine dissolved in 2 mL of distilled water was added dropwise. Once 4-dimethylaminopyridine was added, the mixture was filtered off and allowed to stand at room temperature for one day to produce orange crystals of the title compound [ 27 ].…”

“…Recently, our working team reported a decavanadate compound with DMAPH. The crystal structure of this complex has been completely characterized [ 27 ]. Thus, in this study, our aim was to evaluate the possible metabolic activity of the compound in a dyslipidemia and dysglycemia model, related to insulin signaling in liver and adipose tissue, as well as its toxicological and pharmacological effects.…”