Aims-To compare stereophotographic and monophotographic optic disc assessments made using a digital optic disc stereo camera. Methods-Stereo digital optic disc photographs of 150 selected patients who had presented to a glaucoma clinic were assessed by two masked observers on separate occasions using (1) the stereophotographs and a stereoviewer, (2) a single image from the same stereopair. Results were analysed for both right and left eyes separately. 95% tolerance limits for change (TC) and intraclass correlation coeYcients (ICC) were calculated and a multivariate analysis using a general linear model for repeated measures was performed. Conclusions-This study using a digital stereo camera indicates that there may be little benefit of stereoscopic imaging over monoscopic imaging despite demonstrating small but inconsistent diVerences between both observers and methods. (Br J Ophthalmol 2001;85:1347-1351 The detection of early or progressive glaucomatous optic disc changes is essential in the optimum management of glaucoma patients. Despite the plethora of new technologies the accepted "gold standard" for optic disc assessment remains stereoscopic optic disc photography.
Results-1-4 However, measurements rely on a subjective evaluation by the clinician and are subject to poor interobserver agreement.
5-10The Discam optic disc camera (Marcher Enterprises Ltd, Hereford) obtains digital monochromatic sequential stereophotographic images of the optic disc and the allied software allows the computation of a number of optic disc parameters. In a previous study, the intraobserver and interobserver repeatability of optic disc measurements was shown to compare favourably with ophthalmoscopic and stereophotographic methods of assessment of the optic disc.11 However, stereoscopic versus monoscopic assessments of the images were not performed.The aims of this study were to determine whether there were significant diVerences in intraobserver and interobserver repeatability of the computed optic disc parameters using monophotographic and stereophotographic images to determine the margins of the optic disc and optic cup.
Materials and methodsStereophotographic digital images of patients presenting to a glaucoma clinic were acquired by two experienced operators following pharmacological mydriasis. The detailed method has been previously described. 11 The quality of the images were assessed by observer 2 (MC), on the basis of contrast, clarity, stereoscopic appearance, illumination, and excessive movement between the image pair. As this study did not aim to determine the clinical usefulness of the Discam, but purely to compare two methods of assessment, only high quality images were used for analysis in order to maximise any diVerences. Exclusion criteria were poor illumination of the disc, poor quality image, lens opacity, poor stereoimage (large shift on the screen between images of stereo pair) and optic discs of anomalous configuration (those which were tilted, colobomatous, or myopic). A total of 201 images (from a ...