A New Diphenyl Ether Glycoside from <i>Xylosma longifolium</i> Collected from North-East India

Swapana, Ningombam; Noji, Masaaki; Nishiuma, Rina; Izumi, Masahiro; Imagawa, Hiroshi; Kasai, Yuusuke; Okamoto, Yasuko; Iseki, Kanako; Singh, Chingakham Brajakishor; Asakawa, Yoshinori; Umeyama, Akemi

doi:10.1177/1934578x1701200832

Cited by 3 publications

(7 citation statements)

References 12 publications

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“…Compounds 39 – 45 were confirmed as sugar molecules from comparison of their deprotonated ion mass and fragmentation behaviors with those reported in the literature and online databases [ 47 , 48 , 65 , 66 , 67 , 69 ]. Maltitol, one of the sugar molecules, inhibits Streptococcus mutans DMST 18777, and xylosmaloside has greater antioxidant properties than ascorbic acid [ 70 , 71 ].…”

Section: Resultsmentioning

confidence: 99%

Profiling of Secondary Metabolites of Optimized Ripe Ajwa Date Pulp (Phoenix dactylifera L.) Using Response Surface Methodology and Artificial Neural Network

et al. 2023

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The date palm (Phoenix dactylifera L.) is a popular edible fruit consumed all over the world and thought to cure several chronic diseases and afflictions. The profiling of the secondary metabolites of optimized ripe Ajwa date pulp (RADP) extracts is scarce. The aim of this study was to optimize the heat extraction (HE) of ripe Ajwa date pulp using response surface methodology (RSM) and artificial neural network (ANN) modeling to increase its polyphenolic content and antioxidant activity. A central composite design was used to optimize HE to achieve the maximum polyphenolic compounds and antioxidant activity of target responses as a function of ethanol concentration, extraction time, and extraction temperature. From RSM estimates, 75.00% ethanol and 3.7 h (extraction time), and 67 °C (extraction temperature) were the optimum conditions for generating total phenolic content (4.49 ± 1.02 mgGAE/g), total flavonoid content (3.31 ± 0.65 mgCAE/g), 2,2-diphenyl-1-picrylhydrazyl (11.10 ± 0.78 % of inhibition), and cupric-reducing antioxidant capacity (1.43 µM ascorbic acid equivalent). The good performance of the ANN was validated using statistical metrics. Seventy-one secondary metabolites, including thirteen new bioactive chemicals (hebitol II, 1,2-di-(syringoyl)-hexoside, naringin dihydrochalcone, erythron-guaiacylglycerol-β-syringaresinol ether hexoside, erythron-1-(4′-O-hexoside-3,5-dimethoxyphenyl)-2-syrngaresinoxyl-propane-1,3-diol, 2-deoxy-2,3-dehydro-N-acetyl-neuraminic acid, linustatin and 1-deoxynojirimycin galactoside), were detected using high-resolution mass spectroscopy. The results revealed a significant concentration of phytoconstituents, making it an excellent contender for the pharmaceutical and food industries.

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Section: Resultsmentioning

confidence: 99%

Profiling of Secondary Metabolites of Optimized Ripe Ajwa Date Pulp (Phoenix dactylifera L.) Using Response Surface Methodology and Artificial Neural Network

et al. 2023

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“…Fresh leaves and stem bark extracts are used for ringworm, acne and scabies. The boiled and brewed leaves of this plant are used for curing fever, tuberculosis, inflammation and bronchial disorder [35] . In Ayurveda system of medicine, it is used as an active herb for treatment of insomnia due to its sedative and central nervous system stimulant properties [36] .…”

Section: Botanical Descriptionmentioning

confidence: 99%

“…Several studies reported the presence of active chemical constituents such as glycosides, triterpenoids, flavonoids, sterols, fatty acid and others in different parts of X. longifolia [35,16,[38][39][40] . However, glycoside, triterpenoids, flavonoids, fatty acids and sterols were the main classes of secondary metabolites [16,35,39,41] . The glycosides namely, xylosmaloside was isolated from whole plant [35] whereas xylongoside A and xylongoside B from stem bark of X. longifolia [39] .…”

Section: Phytochemistrymentioning

confidence: 99%

“…However, glycoside, triterpenoids, flavonoids, fatty acids and sterols were the main classes of secondary metabolites [16,35,39,41] . The glycosides namely, xylosmaloside was isolated from whole plant [35] whereas xylongoside A and xylongoside B from stem bark of X. longifolia [39] . Flavonoids like rutin and kaempferol-3-rutinoside were identified in whole plant [40] .…”

Section: Phytochemistrymentioning

confidence: 99%

“…On the other hand, stem bark also contains triterpenoids such as friedelin and epifriedelanol [39,42] . Apart from these compounds, other compounds like methyl caffeate, ethyl β-D -glucopyranoside and roseoside were extracted from whole plant [35] whereas benzoic acid; β-orcinolcarboxylate; 2-(6-benzoyl-β-glucopyranosyloxy)-7-(1α,2α,6α-trihydroxy-5-oxocyclohex-3-enoyl)-5-hydroxybenzyl alcohol, atraric acid, methyl orsellinate, 8-hydroxy-6-methoxypentylisocoumarin and xylosmacin from stem bark [39,42] . Unlike stem bark, previous phytochemical studies revealed that leaves of X. longifolia are the reservoir of secondary metabolites.…”

Section: Phytochemistrymentioning

confidence: 99%

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Morphological, phytochemical and ethnopharmacological attributes of Xylosma longifolia Clos: A review

Ansari¹,

Saleem²,

Asif³

et al. 2023

J Pharmacogn Phytochem

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Xylosma longifolia Clos. (Salicaceae), a medium-sized tree is found mainly in India and China. It is known by different names such as Kattari, Kata-koli, Mota-koli, Kataponial, Nongleishang and Diengkani in different parts of India. It is widely spread in northeast India and also in most parts of China. In India, tribal communities such as ''Miri'' of Assam, ''Kom'' and "Tangkhul" of Manipur, "Lois'' of Imphal, use it to treat cough, spasms, dysentery, insomnia, restlessness, pustules and jaundice. This plant is also enormously used in Ayurveda, Chinese and Vietnamese traditional medicinal systems. The principle compounds reported are xylongoside A, xylongoside B and xylosmaloside. The presence of secondary metabolites imparts its bioactivities including antimicrobial, analgesic, anti-dermatophytic, anti-tubercular, antioxidant and insecticidal activities. To date, not even a single review has been published on X. longifolia. Due to the broad continued interest in the efficacy of X. longifolia and extensive practice in traditional medicines, this review intends to recapitulate detailed and up-to-date information on this plant. The current review assessed and summarized the knowledge on geographic distribution, morphological features, ethnobotany, phytochemistry and pharmacological activities of X. longifolia.

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Xylosma G. Forst. Genus: Medicinal and Veterinary Use, Phytochemical Composition, and Biological Activity

Duarte-Casar

Romero-Benavides

2022

Plants

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Xylosma G. Forst. is a genus of plants belonging to the Salicaceae family with intertropical distribution in America, Asia, and Oceania. Of the 100 accepted species, 22 are under some level of conservation risk. In this review, around 13 species of the genus used as medicinal plants were found, mainly in Central and South America, with a variety of uses, among which antimicrobial is the most common. There is published research in chemistry and pharmacological activity on around 15 of the genus species, centering in their antibacterial and fungicidal activity. Additionally, a variety of active phytochemicals have been isolated, the most representative of which are atraric acid, xylosmine and its derivatives, and velutinic acid. There is still ample field for the validation and evaluation of the activity of Xylosma extracts, particularly in species not yet studied, and concerning uses other than antimicrobial and for the identification and evaluation of their active compounds.

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A New Diphenyl Ether Glycoside from Xylosma longifolium Collected from North-East India

Cited by 3 publications

References 12 publications

Profiling of Secondary Metabolites of Optimized Ripe Ajwa Date Pulp (Phoenix dactylifera L.) Using Response Surface Methodology and Artificial Neural Network

Profiling of Secondary Metabolites of Optimized Ripe Ajwa Date Pulp (Phoenix dactylifera L.) Using Response Surface Methodology and Artificial Neural Network

Morphological, phytochemical and ethnopharmacological attributes of Xylosma longifolia Clos: A review

Xylosma G. Forst. Genus: Medicinal and Veterinary Use, Phytochemical Composition, and Biological Activity

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