A new experimental model for chronic lymphoedema of the extremities (with clinical considerations)

Clodius, L.; Wirth, W

doi:10.1007/bf00302688

Cited by 20 publications

(1 citation statement)

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“…One hind limb was operated on, the contralateral limb serving as control. According to the method of Clodius and Wirth [2], the hind limb was totally transected except the femur, the femoral artery, vein and nerve, and the ischial nerve. The transection of the femoral vessels was performed with the aid of the operating microscope to clean the vessels of all lymphatic tissue and to ligate and mark the transected lymph vessels.…”

Section: Methodsmentioning

confidence: 99%

Experimental basis and first application of clinical lymph vessel transplantation of secondary lymphedema

et al. 1981

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Lymphedemas due to a blockage of the lymph vessels in the root of the extremities were treated experimentally and clinically by autotransplantation of lymph vessels under the operating microscope. In experimental lymphedema of the hind leg of 10 dogs, an increased circumference of about 50% was reduced to 10% within 7 weeks by lymph vessel transplantation. After removal of the transplants, the circumferences returned to pre‐transplantation values. The pre‐transplantation elevated intralymphatic pressure of 12.5 torr (controls: 2.5 torr) was reduced to the normal range of 3.5 torr after the transplantation. In 8 of 10 dogs, the patency of the transplants could be demonstrated by inspection, lymphography, and isotope injections. In all 10 dogs, patency could be proved by histologic examination. The data indicate that lymph vessel transplantation can restore the diminished lymph‐transporting capacity brought on by lymphedema. In 2 patients, it was possible to prepare lymph collectors about 25 cm long. After the transplantation, the circumferences diminished. By isotopes improved lymphatic transport could be demonstrated after the operation. Autologous transplantation of lymph vessels is a promising method for the treatment of secondary lymphedema especially in the early stages.

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Section: Methodsmentioning

confidence: 99%

Experimental basis and first application of clinical lymph vessel transplantation of secondary lymphedema

et al. 1981

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An experimental model for lymphedema in rabbit ear

Gong-Kang

Yuan-Pai

1983

Microsurgery

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A simple, inexpensive method for producing an experimental model for lymphedema in rabbit ear is described. In 47 of 50 rabbit ears, the lymphedema could be demonstrated by measurement of ear thickness, water displacement, skin thickness, diameter of lymphatics, and histopathology of the experimental ear. Three rabbit ears failed because of technical reasons. In studying the findings of experimental lymphedema, some clinical phenomena are explained and modifications of the operative procedure of microlymphaticovenous anastomosis for treating lymphedema are suggested.

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Principles of Vascular Surgery

Rob¹

1985

Cerebrovascular Surgery

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A new experimental model for chronic lymphoedema of the extremities (with clinical considerations)

Cited by 20 publications

References 43 publications

Experimental basis and first application of clinical lymph vessel transplantation of secondary lymphedema

Experimental basis and first application of clinical lymph vessel transplantation of secondary lymphedema

An experimental model for lymphedema in rabbit ear

Principles of Vascular Surgery

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