A New Fe(III) Complex Derived from Cyclohexane Based Imine Derivative: Studies on H₂PO₄⁻ Recognition and Anti‐Cancer Activity Against MCF7 and MDA‐MB‐231 Human Breast Cancer Cells

Abstract

An imine derivative, N,N'-bis-(2-hydroxo-3-ethoxy-benzylidene)cyclohexane-1,2-diamine have been explored for the synthesis of a new Fe(III) complex (F3), the structure of which is confirmed by single crystal X-Ray diffraction ( SC-XRD) analysis. The F3 is very sensitive for selective optical recognition ofThe interaction of F3 with H 2 PO 4 À allows nano-molar (91.17 nM) level detection of H 2 PO 4 À having association constant, 6.92 × 10 4 M À 1 . In addition, F3 is found to have an efficient anti-cancer activity against human breast cancer cell line MCF7 and MDA-MB-231.