A new flavane acid from the fruits of <i>Illicium verum</i>

Wu, Liangdeng; Xiong, Chun-Lan; Chen, Zizhan; He, Ruijie; Zhang, Yanjun; Huang, Yan; Deng, Shengping; Yang, Ronghua; Li, Jun

doi:10.1080/14786419.2015.1120726

Cited by 10 publications

(5 citation statements)

References 19 publications

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“…Anti-fungal, anti-bacterial, antibiotic, analgesic, antispasmodic, analgesic, anti-inflammatory and mosquito symptoms are also present [119] . Some studies have also documented cytotoxic effects 120 , 121 , 122 . Several cell death-related pathways, such as activation of apoptosis, free scavenging, and inhibition of tumor metastasis have been demonstrated.…”

Section: Anti-hepatocellular Carcinoma Effects Of Traditional Chinesementioning

confidence: 99%

WITHDRAWN: Anti-cancer properties of specific Chinese herbal medicines for hepatocellular carcinoma treatment

Zang

Xue

Wang³

et al. 2020

European Journal of Integrative Medicine

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Aims This essay explores the anti-cancer activity of specific Chinese herbal medicines to clarify how effective Chinese herbal medicine is used for handling hepatocellular carcinoma. Methods Literature form publica domain were studied and an analysis of anti-cancer activity of specific Chinese herbal medicines is presented in this review. Results Hepatocellular carcinoma is one of the most dangerous malignant tumors in the world. The operative diagnosis of liver cancer remains a significant challenge. Although surgery tissue resection is encouraging, a high risk of recurrence and metastasis, illustrating disease-related mortality is desperately required to enhance postoperative preventive and therapeutic clinical procedures. The almost only effective clinical intervention seems to be developing advanced targeted therapies such as sorafenib for hepatocellular carcinoma patients, but there is little research in this field. Because their preventative/therapeutic properties strengthen Chinese herbal medicinal compounds, they are deemed relevant to the treatment of hepatocellular carcinoma. Conclusion: Chinese herbal medicine derivates provide multifaceted, orientated and orchestrated therapy, making it an ideal candidate for inhibiting hepatocellular tumor production and metastasis.

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Section: Anti-hepatocellular Carcinoma Effects Of Traditional Chinesementioning

confidence: 99%

WITHDRAWN: Anti-cancer properties of specific Chinese herbal medicines for hepatocellular carcinoma treatment

Zang

Xue

Wang³

et al. 2020

European Journal of Integrative Medicine

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“…We also draw attention of specialists in the food industry to add some of these natural products in different recipes to reduce the probabilities of liver diseases infections. The anti-inflammatory, anti-oxidant, cytotoxic and immunomodulatory [175,176,177,178,179] Illicium verum cytotoxic activity, antioxidant, anti-inflammatory, induction of apoptosis, and inhibition of tumor metastasis [189,190,191,192]…”

Section: Discussionmentioning

confidence: 99%

“…It also possesses antimicrobial, antioxidant, antifungal, analgesic, anti-inflammatory, sedative, insecticidal and anticonvulsive activities [189]. Its cytotoxic activity was also reported in several studies [190][191][192]. It showed numerous mechanisms that involved in cell death such as apoptosis induction, scavenging of free radicals and tumor metastasis inhibition [191].…”

Section: Illicium Verummentioning

confidence: 99%

Herbal management of hepatocellular carcinoma through cutting the pathways of the common risk factors

Abdel-Hamid

Abass

Mohamed

et al. 2018

Biomedicine & Pharmacotherapy

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Hepatocellular carcinoma (HCC) is considered the most frequent tumor that associated with high mortality rate. Several risk factors contribute to the pathogenesis of HCC, such as chronic persistent infection with hepatitis C virus or hepatitis B virus, chronic untreated inflammation of liver with different etiology, oxidative stress and fatty liver disease. Several treatment protocols are used in the treatment of HCC but they also associated with diverse side effects. Many natural products are helpful in the co-treatment and prevention of HCC. Several mechanisms are involved in the action of these herbal products and their bioactive compounds in the prevention and co-treatment of HCC. They can inhibit the liver cancer development and progression in several ways as protecting against liver carcinogens, enhancing effects of chemotherapeutic drugs, inhibiting tumor cell growth and metastasis, and suppression of oxidative stress and chronic inflammation. In this review, we will discuss the utility of diverse natural products in the prevention and co-treatment of HCC, through its capturing of the common risk factors known to lead to HCC and shed the light on their possible mechanisms of action. Our theory assumes that shutting down the risk factor to cancer development pathways is a critical strategy in cancer prevention and management. We recommend the use of these plants side by side to recent chemical medications and after stopping these chemicals, as a maintenance therapy to avoid HCC progression and decrease its global incidence.

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“…The phenolic compound used as carcinogenic inhibitor, and also known for its antioxidant, antibacterial activity as well as antiatherosclerotic agent [24][25][26][27]. 4-Methoxy cinnamic acid possessed antiproliferative activity [28]. It is also used as anti-browning preservative in post harvesting mushroom [29].…”

Section: Lc-ms Analysismentioning

confidence: 99%

Cytotoxic Effect of Ethanol Extract of Abrus precatorius Leaves on Raw 264.7 and SK-N-SH Cell lines

Naduchamy

Parthasarathy

2021

JPRI

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Aim: This study was aimed to investigate the cytotoxic effect of ethanol extract of Abrus precatorius. leaves on Raw 264.7 and SK-N-SH cell lines. Methodology: Soxhlet extraction was carried out using absolute alcohol and subsequently, the profiling of phytoconstituents of ethanol extract was performed by LC-MS analysis. Results: The results showed that the presence of anthocyanin, phenolic acid, carboxylic acid, amino acid and monoester in ethanol extract of Abrus precatorius. The phytoconstituents such as picolinic acid, N-Acetyl-DL-tryptophan, 3-Hydroxybenzoic acid, kuromanin, aflatoxin G2, monobutyl Phthalate, laurolactam, 4-Dodecylbenzenesulfonic acid, 4-Methoxycinnamic acid, caffeic acid and octyl decyl phthalate were found in ethanol extract. In addition to this, the cytotoxic effect of the ethanol extract was tested on Raw 264.7 and SK-N-SH cell lines using MTT assay. The cytotoxic study revealed that the ethanol extract of Abrus precatorius was non-toxic to Raw 264.7 cell, but it showed a toxic effect on human neuroblastoma cell line, SK-N-SH. Conclusion: In this study, it was observed that the ethanol extract of Abrus precatorius was non-toxic to Raw 264.7 cell line, but it exhibited strong inhibition on the viability of SK-N-SH cell line.

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A new flavane acid from the fruits of Illicium verum

Cited by 10 publications

References 19 publications

WITHDRAWN: Anti-cancer properties of specific Chinese herbal medicines for hepatocellular carcinoma treatment

WITHDRAWN: Anti-cancer properties of specific Chinese herbal medicines for hepatocellular carcinoma treatment

Herbal management of hepatocellular carcinoma through cutting the pathways of the common risk factors

Cytotoxic Effect of Ethanol Extract of Abrus precatorius Leaves on Raw 264.7 and SK-N-SH Cell lines

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