A New Flavonoid fromLimonium axillare

Kandil, F. E.; Ahmed, Khadiga M.; Hussieny, H. A.; Soliman, Ahmed M.

doi:10.1002/1521-4184(20008)333:8<275::aid-ardp275>3.0.co;2-4

Cited by 19 publications

(2 citation statements)

References 6 publications

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“…( Morgan and Funnell, 2018 ; González-Orenga et al., 2021 ). Other species have ethnopharmacological uses against several ailments, including cardiovascular and inflammatory conditions, ( Aniya et al., 2002 ; Murray et al., 2004 ; González-Orenga et al., 2021 ), are rich in bioactive polyphenolic compounds, in particular flavonoids ( Lin and Chou, 2000 ; Ye and Huang, 2006 ; Geng et al., 2015 ), and display several functional properties, such as antioxidant, anti-inflammatory and immunomodulation ( Kandil et al., 2000 ; Aniya et al., 2002 ; Kuo et al., 2002 ; Mahasneh, 2002 ; Murray et al., 2004 ; Cantrell et al., 2007 ; Smirnova et al., 2009 ; Lee et al., 2011 ; Nostro et al., 2012 ; Tang et al., 2012 ; Saidana et al., 2013 ; Ali et al., 2013 ; Rodrigues et al., 2015 ; Souid et al., 2019 ).…”

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confidence: 99%

Nutritional anti-nutritional chemical composition and antioxidant activities of the leaves of the sea cliff dwelling species Limonium spathulatum (Desf.) Kuntze

et al. 2022

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This work explored the nutritional and antioxidant properties of the leaves of the halophytic species Limonium spathulatum (Desf.) Kuntze from Tunisian sea cliffs. Furthermore, the analysis of the total phenolics and flavonoids contents and their individual compounds using high-performance liquid chromatography coupled with electrospray ionization mass spectrometry (HPLC-ESI-MS/MS) were also studied. L. spathulatum leaves had high levels of moisture, ash, neutral detergent fiber, and acid detergent fiber, but low concentrations of crude protein, crude fat and acid detergent lignin. It contained low carbohydrates levels, and low energetic values. The most abundant macroelements were Cl, Na and Ca while the microelements detected in the highest levels were Fe and Zn. No relevant α-amylase inhibition was observed, and no toxic metals (Pb and Cd) and phytic acid were detected. The ethanol and the hydroethanolic extracts had the highest capacity to scavenge free radicals, to chelate iron and copper and to inhibit lipid peroxidation. The same samples were also the most active towards oxidative haemolysis. These extracts contained high total phenolic and flavonoid contents. HPLC analysis, performed on ethanolic extracts identified 58 individual compounds known for their high antioxidant actvitiy including hydroxybenzoic acids (gallic, syringic acids), hydroxycinnamic acids (caffeic, coumaric, ferulic acids) and flavonoids (catechin, epigallocatechin gallate and naringin).In conclusion, the leaves of Tunisian accession of L. spathulatum were good source of minerals and fibers useful in the human diet for attaining nutritional sufficiency. The high in vitro and ex vitro antioxidant activities associated with high favonoids contents and compounds suggest the possibility to use the extracts of L. spathulatum in herbal products with the aim of improving general health and well-being, and/or as food additives for preventing lipid oxidation of lipid-rich foods.

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Section: Introductionmentioning

confidence: 99%

Nutritional anti-nutritional chemical composition and antioxidant activities of the leaves of the sea cliff dwelling species Limonium spathulatum (Desf.) Kuntze

et al. 2022

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“…C) of compounds 1 and 2, and the chemical shifts (Dd C ) for sugar carbons by comparison with 3.N.-N. Kong et al 372 determined as quercetin-3-O-(3 00 -Otigloyl)-a-L-rhamnopyranoside. In addition to the above-mentioned new flavonoids, 10 known compounds including quercetin-3-O-a-L-rhamnopyranoside (3) [13], myricetin-3-O-(2 00 -O-galloyl)-a-Lrhamnopyranoside (4) [5,14,15], myricetin-3-O-(3 00 -O-galloyl)-a-L-rhamnopyranoside (5) [5,15], myricetin-3-O-a-L-rhamnopyranoside (6) [16], kaempferol-3-O-a-L-rhamnopyranoside (7)[17], apigenin (8)[13], luteolin(9)…”

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Two new flavonoid glycosides from the halophyte Limonium franchetii

Kong

Fang

Wang

et al. 2014

Journal of Asian Natural Products Research

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Two new flavonoid glycosides, named quercetin-3-O-(2″-O-tigloyl)-α-L-rhamnopyranoside (1) and quercetin-3-O-(3″-O-tigloyl)-α-L-rhamnopyranoside (2), together with 10 known flavonoids (3-12), were isolated from the whole plant of the halophyte Limonium franchetii. Their structures were elucidated on the basis of extensive spectroscopic analysis including 2D NMR and HR-EI-MS. In addition, primary bioassays showed that compound 1 had moderate cytotoxic activity against rat C6 glioma cell lines.

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