A new fluorescent sensor for determination of thorium by thin film of 2-(acetyloxy)-N-(5-nitro-2-thiazolyl)-benzamide embedded in sol–gel matrix

Elabd, A. A.

doi:10.1039/c6ra04226k

Cited by 21 publications

(10 citation statements)

References 49 publications

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“…Since a benzyl part of ET molecule enter probably to a hydrophobic cavity of calixarene skeleton, stoichiometric ratio of inclusion complex formation between ET and SC4 should be theoretically 1:1. This theory can be proved if a linear relationship is obtained from the reciprocal plot of 1/F vs. 1/[Q] based on the modified Hildebrand-Benesi Equation [29]. Figure 7a shows reciprocal plots that determine a stoichiometric ratio of an inclusion complex formation.…”

Section: Resultsmentioning

confidence: 98%

Intermolecular interactions and binding mechanism of inclusion complexation between sulfonate calix[n]arenes and ethidium bromide

Bayrakcı

Yılmaz

2018

J Incl Phenom Macrocycl Chem

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In this work, the interactions between ethidium bromide (ET) and water-soluble sulfonate calix[n]arenes (n: 4, 6, and 8) were investigated by NMR, FT-IR, and fluorescence spectroscopic methods. The aim was to evaluate both the stoichiometry and the mechanism of the possible complex structure between sulfonate calix[n]arenes and ET. The spectroscopic data revealed that a 1:1 binding mode between calixarene and ET was occurred. Furthermore, thermodynamic parameters and fluorescence titration experiments were studied at different temperatures to determine both the quenching mechanism and the type of intermolecular forces in complex formation. Host-guest complexation of sulfonate calix[n]arenes and ET could be used to overcome some adverse effects related to the using of ethidium bromide during biological applications as a DNA marker treatment.

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Section: Resultsmentioning

confidence: 98%

Intermolecular interactions and binding mechanism of inclusion complexation between sulfonate calix[n]arenes and ethidium bromide

Bayrakcı

Yılmaz

2018

J Incl Phenom Macrocycl Chem

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“…Also, this theory can be supported by the modified Hildebrand-Benesi Equation if a linear relationship gained from the reciprocal plot of 1/F-F 0 vs. 1/[Q]. [23] Reciprocal plots helping the determination of the stoichiometry ratio for the complex formation are given in Figure 7. From curve fitting of probe C4PA fluorescence intensity against the reciprocal of the Yb 3C concentration, Benesi-Hildebrand equation plot shows a linear fit.…”

Section: Spectroscopic Studiesmentioning

confidence: 90%

Macrocyclic anthracene-anchored calix[4]arene as a sensitive and selective fluorescent chemosensor for ytterbium ions

Yılmaz

Bayrakcı

2018

Journal of Macromolecular Science, Part A

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A novel anthracene anchored cone calix[4]arene pyridine amide receptor C4PA was synthesized and characterized by combination of spectroscopic and spectrophotometric techniques. Ion binding properties of C4PA towards a series of metal cations were investigated by UV and fluorescence spectra. A remarkable increase for receptor C4PA in fluorescence intensity in the presence of trace amounts of Yb 3C was observed. C4PA showed "turn on" type fluorescence response toward Yb 3C with high selectivity and C4PA also retained its selectivity toward Yb 3C in the presence of most competing metal ions.

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“…The binding constants (KB) for MMP@HSA and MPA@HSA complexes were determined using the modified Benesi-Hildebrand equation [13], where the stoichiometry of the complex was taken as 1, according to the Job-plot curves (Figure S1 in Supporting Information) [14] 1 −…”

Section: Photophysical Properties Of Mmp and Mpa Within Hsamentioning

confidence: 99%

“…This indicates very poor binding of MPA to HAAG. Again, KB was determined using the modified Benesi-Hildebrand equation [13] (taking into account a 1:1 stoichiometry for the complex, determined from the Job plot, shown in the Supporting information) [14]. Thus, KB was determined as 1.1 × 10 4 M -1 .…”

Section: Photophysical Properties Of Mmp and Mpa In Haagmentioning

confidence: 99%

A combined photophysical and computational study on the binding of mycophenolate mofetil and its major metabolite to transport proteins

Vendrell-Criado

González‐Bello

Miranda

et al. 2018

Spectrochimica Acta Part A: Molecular and Biomolecular Spectros

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Binding of the immunosuppressive agent mycophenolate mofetil (MMP) and its pharmacologically active metabolite mycophenolic acid (MPA) to human serum albumin (HSA) and α-acid glycoprotein (HAAG) has been investigated by means of an integrated approach involving selective excitation of the drug fluorophore, following their UV-A triggered fluorescence and docking studies. The formation of the protein/ligand complexes was evidenced by a dramatic enhancement of the fluorescence intensity and a hypsochromic shift of the emission band. In HSA, competitive studies using oleic acid as site I probe revealed site I as the main binding site of the ligands. Binding constants revealed that the affinity of the active metabolite by HSA is four-fold higher than its proactive form. Moreover, the affinity of MMP by HSA is three-fold higher than by HAAG. Docking studies revealed significant molecular binding differences in the binding of MMP and MPA to sub-domain IIA of HSA (site 1). For MPA, the aromatic moiety would be in close contact to Trp214 with the flexible chain pointing to the other end of the sub-domain; on the contrary, for MMP, the carboxylate group of the chain would be fixed nearby Trp214 through electrostatic interactions with residues Arg218 and Arg222.

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A new fluorescent sensor for determination of thorium by thin film of 2-(acetyloxy)-N-(5-nitro-2-thiazolyl)-benzamide embedded in sol–gel matrix

Abstract: A new “turn-off” fluorescent sensor for determination of thorium (Th(iv)) by thin film of 2-(acetyloxy)-N-(5-nitro-2-thiazolyl)-benzamide (L) embedded in sol–gel matrix was introduced.

Cited by 21 publications

References 49 publications

Intermolecular interactions and binding mechanism of inclusion complexation between sulfonate calix[n]arenes and ethidium bromide

Intermolecular interactions and binding mechanism of inclusion complexation between sulfonate calix[n]arenes and ethidium bromide

Macrocyclic anthracene-anchored calix[4]arene as a sensitive and selective fluorescent chemosensor for ytterbium ions

A combined photophysical and computational study on the binding of mycophenolate mofetil and its major metabolite to transport proteins

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