In the article, the medicinal properties, botanical description of the promising medicinal plant Hypericum perforatum species are studied, and the morpho-biological characteristics of the Hypericum perforatum species in the gray soils of Samarkand region are based on the comparative aspect. Depending on the planting conditions and periods of Hypericum perforatum, the seed yield, phytomass yield was determined, and recommendations for the cultivation of quality seeds and raw materials were developed.