A new hemostatic puncture closure device for the immediate sealing of arterial puncture sites

Sheath pulling immediately after PTCA: Comparison of two different deployment techniques for the hemostatic puncture closure device: A prospective, randomized study

“…HPCD proved to be safe and effective with a significant reduction in time to hemostasis from 19.6 6 12.6 to 3.5 6 8.5 min [11]. These data were consistent with earlier findings from nonrandomized or general reports on patients after diagnostic and interventional procedures [8,36,37].…”

“…For HPCD, the data are sparse regarding hemostasis when sheaths are pulled immediately after PTCA: De Swart et al reported 16 patients with immediate sheath pulling after PTCA [8]; time to hemostasis, however, was mixed with patients undergoing diagnostic catheterization. In the US multicenter trial, sheaths were pulled after approximately 8 hr (465 6 523 min) in the 46 patients assigned to HPCD at an ACT of 213 6 89 sec [11].…”

“…Finally, a spring is attached between the tamper and a metal tag fixed to the positioning suture, thus applying continuous pressure on the tamper. The technique of deployment has been described in detail elsewhere [8,11]. It usually takes less than 60 sec to deploy the HPCD.…”

“…With the development of new sealing devices for closing femoral arterial puncture sites, immediate sheath pulling in anticoagulated patients with a low risk of bleeding complications became reality [1][2][3][4][5][6][7][8]. Whereas the administration of the vascular hemostatic device (VHD) on the surface of the arterial puncture site [9] as well as the application of a suture-mediated closure device [10] are straightforward (using deployment techniques with standardized application protocols), the use of the hemostatic puncture closing device (HPCD) [11] allows several possibilities regarding its deployment time (DT): the recommended DT of 30 minutes [11] leads to a prolonged stay in the catheterization laboratory facilities, slowing down the transfer of the patients to the intermediate care unit.…”

Reduction of femoral artery bleeding post catheterization using a collagen enhanced fibrin sealant

“…One clinical study found a higher rate of access site complications when comparing this device to the conventional manual compression method, including an increased incidence of femoral artery occlusions due to intra-arterial placement of collagen material [27]. The other collagen plug system currently under clinical investigation contains a relatively small amount of collagen in comparison (6 16 mg vs. 6 180 mg) [29], but this system requires an additional device to anchor the plug to the arterial wall. According to one clinical study, this anchoring device failed to deploy properly in 3 out of 32 attempts (9%) [30].…”