A new insight on nanomagnet–porphyrin hybrids for photodynamic inactivation of microorganisms

Alves, Eliana; Rodrigues, João; Faustino, Maria A. F.; Neves, Maria G. P. M. S.; Cavaleiro, José A. S.; Lin, Zhi; Cunha, Ângela; Nadais, Helena; Tomé, João P. C.; Almeida, Adelaide

doi:10.1016/j.dyepig.2014.05.016

Cited by 71 publications

(41 citation statements)

References 34 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In order to use this approach in operative field conditions, the multi-charged nanomagnet-Tri-Py + -Me-PF hybrid has been recently tested [111]. Preliminary results showed that this hybrid is effective in Allivibrio fischeri photoinactivation in, at least, a sixcycle reuse, causing a cumulative bacterial reduction higher than 37 log under low light irradiance (4.0 mW cm −2 ).…”

Section: Water Disinfectionmentioning

confidence: 99%

“…No [47] No [50,52,69] On filter paper [82] On cotton fabric [86,108] On polysilsesquioxane plastic films [61] On cotton fabric [87] On azide-modified cellulose nanocrystals [43,75] On chloroacetyl cellulose ester chlorides [78] On cellulose laurate esters plastic films [79] No [71] No [93] No [49,71,93,110] and Tri-Py + -Me-PF on silica coated Fe3O4 nanoparticles [70] and also on CoFe2O4 nanoparticles [111] No [81] No [105] No [36,37,71,74,81,105]; Tetra-Py + -Me was entrapped into microporous silica gels [88] and into three alkylene-bridged polysilsesquioxanes [89] On optically transparent indium tin oxide electrodes [63] On chitosan membranes [72] Pd(II) TetraTPPCO2H On a polyurethane matrix [83] No [105] In hydrophilic polycaprolactone and polyurethane (TecophilicH) nanofibers [60]; on electrospun polymeric nanofiber materials polyurethane Larithane TM , polystyrene, polycaprolactone, and polyamide 6 [76]; into three alkylene-bridged polysilsesquioxanes [89]; and in a silica-gel supported antimony porphyrin complex SbTPP [97,98] No [44,…”

Section: Porphyrinmentioning

confidence: 99%

See 1 more Smart Citation

Potential applications of porphyrins in photodynamic inactivation beyond the medical scope

Alves

Faustino

Neves

et al. 2015

Journal of Photochemistry and Photobiology C: Photochemistry Re

Self Cite

198

128

View full text Add to dashboard Cite

a b s t r a c tAlthough the discovery of light-activated antimicrobial agents had been reported in the 1900s, only more recently research work has been developed toward the use of photodynamic process as an alternative to more conventional methods of inactivation of micro(organisms). The photoprocess causes cell death through irreversible oxidative damage by reactive oxygen species produced by the interaction between a photosensitizing compound and a light source.With great emphasis on the environmental area, photodynamic inactivation (PDI) has been tested in insect eradication and in water disinfection. Lately, other studies have been carried out concerning its possible use in aquaculture waters or to the control of food-borne pathogens. Other potential applications of PDI in household, industrial and hospital settings have been considered.In the last decade, scientific research in this area has gained importance not only due to great developments in the field of materials chemistry but also because of the serious problem of the increasing number of bacterial species resistant to common antibiotics. In fact, the design of antimicrobial surfaces or selfcleaning materials is a very appealing idea from the economic, social and public health standpoints. Thus, PDI of micro(organisms) represents a promising alternative.In this review, the efforts made in the last decade in the investigation of PDI of (micro)organisms with potential applications beyond the medical field will be discussed, focusing on porphyrins, free or immobilized on solid supports, as photosensitizing agents.

show abstract

Section: Water Disinfectionmentioning

confidence: 99%

Section: Porphyrinmentioning

confidence: 99%

Potential applications of porphyrins in photodynamic inactivation beyond the medical scope

Alves

Faustino

Neves

et al. 2015

Journal of Photochemistry and Photobiology C: Photochemistry Re

Self Cite

198

128

View full text Add to dashboard Cite

show abstract

“…magnetite-silica core/shell nanoparticles [25,26] or via carbodiimide activation [27,28]. These hybrids were evaluated as antibacterial agents [26,29], as photocatalysts [30], as magnetic heavy metal ions adsorbents [27], and as adsorbents for polycyclic aromatic hydrocarbons from water samples [31]. The preparation of porphyrin-magnetite hybrids prompted us to perform the chemical synthesis of hybrids composed of magnetite nanoparticles and a corrolic macrocycle.…”

Section: Resultsmentioning

confidence: 99%

“…Other studies have reported the use of a silica shell as the key to promote the chemical grafting between porphyrin and magnetite nanoparticles, e.g., by nucleophilic substitution of crucial porphyrinic groups with the amino surface of magnetite-silica core/shell nanoparticles [25,26] or via carbodiimide activation [27,28]. These hybrids were evaluated as antibacterial agents [26,29], as photocatalysts [30], as magnetic heavy metal ions adsorbents [27], and as adsorbents for polycyclic aromatic hydrocarbons from water samples [31].…”

Section: Introductionmentioning

confidence: 99%

Magnetite–Corrole Hybrid Nanoparticles

2018

View full text Add to dashboard Cite

This study describes the first example of a hybrid material comprising corroleand silica-coated magnetite nanoparticles. Firstly, cuboid and spheroid magnetite nanoparticles were prepared using a simple hydrothermal route, followed by a silica coating. The hybrid nanoparticles were obtained by promoting a covalent link between a gallium (III)(pyridine) complex of 5,10,15-tris(pentafluorophenyl)corrole (GaPFC) and the surface of magnetite-silica core/shell nanoparticles (Fe 3 O 4 @SiO 2 ), shaped both as cuboids and spheroids. The hybrids were characterized using Fourier transform infrared spectroscopy (FTIR), X-ray diffraction (XRD), ultraviolet-visible spectrophotometry (UV-Vis) and transmission electron microscopy (TEM). Preliminary studies on the capacity of singlet oxygen generation of the hybrid nanoparticles showed that these have lower efficiency values when compared to the pure corrole compound.

show abstract

“…[1][2][3][4][5][6][7][8][9] Currently, mesoporous and amorphous SNP have been extensively used in the biomedical eld. 9,10 While mesoporous SNP are normally used as drug delivery systems through physical or chemical adsorption, colloidal SNP have been often employed to encapsulate or to graft at the surface active agents. 12,13 In the past decades, the increasing need to understand the biological processes and environment in°uences of therapeutic compounds inside biologic systems, led to an increasing search for new bioimaging systems capable of overcoming the limitations of current biomarkers.…”

Section: Introductionmentioning

confidence: 99%

The role of surface functionalization of silica nanoparticles for bioimaging

Gomes

Trindade

Tomé

2016

J. Innov. Opt. Health Sci.

Self Cite

View full text Add to dashboard Cite

Among the several types of inorganic nanoparticles available, silica nanoparticles (SNP) have earned their relevance in biological applications namely, as bioimaging agents. In fact,°uorescent SNP (FSNP) have been explored in this¯eld as protective nanocarriers, overcoming some limitations presented by conventional organic dyes such as high photobleaching rates. A crucial aspect on the use of°uorescent SNP relates to their surface properties, since it determines the extent of interaction between nanoparticles and biological systems, namely in terms of colloidal stability in water, cellular recognition and internalization, tracking, biodistribution and specicity, among others. Therefore, it is imperative to understand the mechanisms underlying the interaction between biosystems and the SNP surfaces, making surface functionalization a relevant step in order to take full advantage of particle properties. The versatility of the surface chemistry on silica platforms, together with the intrinsic hydrophilicity and biocompatibility, make these systems suitable for bioimaging applications, such as those mentioned in this review.

show abstract

A new insight on nanomagnet–porphyrin hybrids for photodynamic inactivation of microorganisms

Cited by 71 publications

References 34 publications

Potential applications of porphyrins in photodynamic inactivation beyond the medical scope

Potential applications of porphyrins in photodynamic inactivation beyond the medical scope

Magnetite–Corrole Hybrid Nanoparticles

The role of surface functionalization of silica nanoparticles for bioimaging

Contact Info

Product

Resources

About