Although the well-known differential transform method (DTM) is one of the effective methods for
solving single-interval boundary value problems (SIBVPs), this method cannot be directly applied to multi-intervalboundary value transmission problems (MIBVTPs). In this study, we generalized the classical DTM so that it can be applied to solving not only SIBVPs but also MIBVTPs. To justify the effectiveness of the presented generalization of DTM, we solved two MIBVTPs for the three-interval differential equations and graphically compared the obtained approximate solutions with the corresponding exact solutions.