A New Marker Evaluating the Risk of Ischemic Bowel in Incarcerated Hernia: Immature Granulocytes

Şenlikçi, Abdullah; Koşmaz, Koray; Durhan, Abdullah; Suner, Mert Orhan; Bezirci, Rıfat; Mercan, Umit; Süleyman, Marlen

doi:10.1007/s12262-021-03014-7

Cited by 2 publications

(2 citation statements)

References 14 publications

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“…The new-generation hemogram devices used in recent years can calculate the number and percentage of immature granulocytes, thus enabling them to be used as an easily and quickly accessible marker without requiring additional costs. There are many studies indicating the prognostic importance of immature granulocyte in patients with sepsis and bacteremia in the literature 5,[20][21][22][23] . Soh et al conducted a study on patients who applied to the emergency department with abdominal pain complaint and stated that immature granulocyte value should be considered in terms of making an emergency abdominal surgery decision or in terms of peritonitis 24 .…”

Section: Discussionmentioning

confidence: 99%

Role of immature granulocytes and total bilirubin values in the diagnosis of perforated appendicitis in patients over 65 years

Altıner

Cebeci

Sucu

et al. 2022

Rev. Assoc. Med. Bras.

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OBJECTIVE:The aim of this study was to investigate the effectiveness of immature granulocyte count, immature granulocyte percentage, and total bilirubin value in predicting complicated and perforated appendicitis in patients aged 65 years and older with a diagnosis of appendicitis. METHODS: In this study, 84 patients, aged 65 years and older, who had appendectomy demographic information, preoperative white blood cell count, neutrophil/lymphocyte ratio, immature granulocyte count and immature granulocyte percentage, operation findings, and pathology results were collected retrospectively. They were grouped into 4 categories: complicated, non-complicated, perforated, and non-perforated, according to the data and surgical findings. RESULTS: Total bilirubin and immature granulocyte count were found to be statistically significant in predicting complicated and perforated appendicitis in patients aged 65 years and older with a diagnosis of appendicitis. The total bilirubin was found to have the following values in differentiating complicated appendicitis: area under the curve=0.883, sensitivity=78.3%, and specificity=88.5%. Total bilirubin had the highest discrimination power with area under the curve=0.804 in differentiating perforation. CONCLUSION: The immature granulocyte percentage and total bilirubin count are the fast, inexpensive, and reliable parameters that can be used to predict complicated and perforated appendicitis in patients aged 65 years and older.

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Section: Discussionmentioning

confidence: 99%

Role of immature granulocytes and total bilirubin values in the diagnosis of perforated appendicitis in patients over 65 years

Altıner

Cebeci

Sucu

et al. 2022

Rev. Assoc. Med. Bras.

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“…Dogan et al [20] demonstrated that acute appendicitis patients with higher IG levels could have a higher possibility of perforation. Senlikci et al [21] revealed that IG and IG% values were significant for evaluating the presence of ischemic bowel in irreducible inguinal hernias.…”

Section: Discussionmentioning

confidence: 99%

The role of immature granulocyte in the early prediction of gastrointestinal tract perforations

DURAK>

Turhan

2022

J Surg Med

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Background/Aim: Gastrointestinal system (GIS) perforations cause acute abdomen an indication for emergency intervention. Early detection is very important in gastrointestinal perforations to prevent mortality and morbidity. This study aimed to examine whether immature granulocyte (IG) and IG percentages (IG%) can be used as a simple and easy marker for identifying gastrointestinal system perforations early on. Methods: Between January 1, 2020, and January 1, 2022, 120 patients who presented to Hitit University Erol Olçok Training and Research Hospital's emergency service and underwent surgery on by the General Surgery Clinic with the diagnosis of the acute abdomen were investigated. The patients were divided into two groups. Patients in group 1 included those with peptic ulcers and bowel perforations. Group 2 was considered the control group. Of the 36 patients in group 2, 22 had acute appendicitis, 12 had ileus-related bridectomy or bowel resection, and two had acute cholecystitis. The common patient feature in this group was full-thickness or serosal iatrogenic bowel injury and repair. Pre-operative IG and IG% values were obtained from routine complete blood count values. IG and IG% values were compared between groups 1 and 2, and the predictive value of these biomarkers in the early diagnosis of GIS perforations was investigated. Results: The mean age of the patients was 55.49 (19.58). The study consisted of 45 (37.5%) female patients and 75 (62.5%) male patients. Group 1 had 84 patients, whereas Group 2 had 36. When the two groups were evaluated, the IG value was higher in Group 1 (P < 0.001). In terms of the percentage value of immature granulocytes, a statistically significant difference was found between Groups 1 and 2 (P = 0.001). As a result, Group 1's IG and IG% values were much greater than those in Group 2. Conclusion: IG and IG% values are inflammatory parameters that can be easily studied in routine hematology tests. According to this study, IG and IG% values were found to be higher in gastrointestinal tract perforations based on result blood tests taken at the time of admission to the emergency department.

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A New Marker Evaluating the Risk of Ischemic Bowel in Incarcerated Hernia: Immature Granulocytes

Cited by 2 publications

References 14 publications

Role of immature granulocytes and total bilirubin values in the diagnosis of perforated appendicitis in patients over 65 years

Role of immature granulocytes and total bilirubin values in the diagnosis of perforated appendicitis in patients over 65 years

The role of immature granulocyte in the early prediction of gastrointestinal tract perforations

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