A New Metabolic Mechanism for Absence of Pain in Patients with Silent Myocardial Ischemia

El-Aziz, Tarek A. Abd; Hussein, Yousri M.; Elsebaie, Maha Hamed; Mohammad, Hany A.; Mohamed, Randa H.

doi:10.1016/j.arcmed.2015.01.003

Cited by 1 publication

(1 citation statement)

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“…According to the investigation, the stimulator of the ischemic pain of the heart is the lactate. Elevation of its level leads to the activation of pain receptors and the chest pain [Abd El-Aziz, 2015].…”

Section: Introductionmentioning

confidence: 99%

Coronary Disease Risk in Asymptomatic Patients with Left Ventricular Moderate Dilatation

Solomon

Andro

Nikolozi

2021

ESJ

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Goal of the Study is to assess the risk of coronary disease of asymptomatic ischemia in patients with left ventricular moderate dilatation. Methods: The work was based on the results of investigation of 185patients with left ventricular moderate dilatation, aged 35-55 years from the “Tbilisi Heart and Vascular Clinic” contingent. Among them, there are 159 men and 26 women. Results: Patients who suffer from left ventricular moderate dilatation and don’t expose typical symptom of ischemia possibly are in risk of carrying damaged coronary artery. the LV moderate dilatation of the left ventricle can be used for primary diagnosing of silent ischemia. Sensitivity - 0.867(95%CI:0.806-0.927); Specificity – 0.800(95%CI:0.703-0.897); Prognostic value of positive results; 0.889(95%CI:0.832-0.946); Prognostic value of negative results - 0.765(95%CI:0.664-0.866); diagnostic value - 0.843(95%CI:0.791-0.896). Conclusions: In patients with silent ischemia, the coronary disease predictors are: left ventricular moderate dilatation, male gender, dyslipidemia, arterial hypertension, smoking, positive treadmill test, ischemic disease in 1st degree relatives, low tolerance to treadmill test. Thus, we can use the moderate dilatation of the left ventricle for the primary diagnosing of silent ischemia. The test is simple and non-invasive. It is characterized by high sensitivity and specificity and can be used for early diagnosing of silent ischemia and the prevention of cardiac cases.

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Section: Introductionmentioning

confidence: 99%