A new method for analysis of non‐pregnant uterine peristalsis using transvaginal ultrasound

Meirzon, D.; Jaffa, Ariel J.; Gordon, Zoya; Elad, David

doi:10.1002/uog.8950

Cited by 22 publications

(23 citation statements)

References 15 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The tongue kinematics was analyzed from in vivo submental ultrasound video clips. The computational methods were similar to those used in our previous studies where we converted video clips of medical images into time-dependent biological data that can be analyzed in the time-frequencyspace domains for the enhancement of physiological knowledge (Elad et al, 2014;Eytan et al, 1999;Gora et al, 2016Gora et al, , 2018Meirzon et al, 2011;Zhang et al, 2019). The experimental and objective computational approach to explore tongue kinematics during infant feeding or adult swallowing is schematically shown in the flow chart depicted in Figure 1.…”

Section: Methodsmentioning

confidence: 99%

Quantitative imaging of tongue kinematics during infant feeding and adult swallowing reveals highly conserved patterns

Genna¹,

Saperstein

Siegel

et al. 2021

Physiol Rep

View full text Add to dashboard Cite

Tongue motility is an essential physiological component of human feeding from infancy through adulthood. At present, it is a challenge to distinguish among the many pathologies of swallowing due to the absence of quantitative tools. We objectively quantified tongue kinematics from ultrasound imaging during infant and adult feeding. The functional advantage of this method is presented in several subjects with swallowing difficulties. We demonstrated for the first time the differences in tongue kinematics during breast‐ and bottle‐feeding, showing the arrhythmic sucking pattern during bottle‐feeding as compared with breastfeeding in the same infant with torticollis. The method clearly displayed the improvement of tongue motility after frenotomy in infants with either tongue‐tie or restrictive labial frenulum. The analysis also revealed the absence of posterior tongue peristalsis required for safe swallowing in an infant with dysphagia. We also analyzed for the first time the tongue kinematics in an adult during water bolus swallowing demonstrating tongue peristaltic‐like movements in both anterior and posterior segments. First, the anterior segment undulates to close off the oral cavity and the posterior segment held the bolus, and then, the posterior tongue propelled the bolus to the pharynx. The present methodology of quantitative imaging revealed highly conserved patterns of tongue kinematics that can differentiate between swallowing pathologies and evaluate treatment interventions. The method is novel and objective and has the potential to advance knowledge about the normal swallowing and management of feeding disorders.

show abstract

Section: Methodsmentioning

confidence: 99%

Quantitative imaging of tongue kinematics during infant feeding and adult swallowing reveals highly conserved patterns

Genna¹,

Saperstein

Siegel

et al. 2021

Physiol Rep

View full text Add to dashboard Cite

show abstract

“…Differences in thickness among uterine segments can also represent other patterns of uterine activity as peristalsis (37, 38, 51), which has been previously associated with placental detachment (52). Uterine peristalsis has been described using ultrasound and MRI techniques in non-pregnant women (53-65) as inherent, subtle, and rhythmic movements in the endometrium and the innermost zone of the myometrium (54) that is hormonally stimulated (56, 57, 66, 67). In women with endometriosis uncoordinated and arrhythmic uterine contractions have been described as “hyperperistalsis or dysperistalsis” (67, 68).…”

Section: Discussionmentioning

confidence: 99%

Dynamic Changes in the Myometrium during the Third Stage of Labor, Evaluated Using Two-Dimensional Ultrasound, in Women with Normal and Abnormal Third Stage of Labor and in Women with Obstetric Complications

Patwardhan

Hernández‐Andrade

Ahn

et al. 2015

Gynecol Obstet Invest

View full text Add to dashboard Cite

Objective: To investigate dynamic changes in myometrial thickness during the third stage of labor. Methods: Myometrial thickness was measured using ultrasound at one-minute time intervals during the third stage of labor in the mid-region of the upper and lower uterine segments in 151 patients including: women with a long third stage of labor (n = 30), postpartum hemorrhage (n = 4), preterm delivery (n = 7) and clinical chorioamnionitis (n = 4). Differences between myometrial thickness of the uterine segments and as a function of time were evaluated. Results: There was a significant linear increase in the mean myometrial thickness of the upper uterine segments, as well as a significant linear decrease in the mean myometrial thickness of the lower uterine segments until the expulsion of the placenta (p < 0.001). The ratio of the measurements of the upper to the lower uterine segments increased significantly as a function of time (p < 0.0001). In women with postpartum hemorrhage, preterm delivery, and clinical chorioamnionitis, an uncoordinated pattern among the uterine segments was observed. Conclusion: A well-coordinated activity between the upper and lower uterine segments is demonstrated in normal placental delivery. In some clinical conditions this pattern is not observed, increasing the time for placental delivery and the risk of postpartum hemorrhage.

show abstract

“…The objective computerized analysis of TVUS video clips revealed motility of the FEI with amplitudes of 0.01–0.19 mm and frequencies of 0.005–0.09 Hz during days 10–16 . More recently, it has been shown that the EMI motility has amplitudes of 0.6–2.0 mm and frequencies of 0.029–0.087 Hz …”

Section: Uterine Peristalsismentioning

confidence: 99%

“…Contractility of smooth muscle depends on levels of hormones, and accordingly, their characteristics vary during the menstrual cycle. Many studies of human uterine peristalsis revealed cervix‐to‐fundus directed contractions at rates of 1–5 contraction/min during the proliferative and secretory phases, while during the menstrual phase the direction is reversed with smaller rates of 0.5–2.5 contraction/min and larger amplitudes …”

Section: Uterine Peristalsismentioning

confidence: 99%

“…Registration of the images with respect to the fundal end enabled analysis of the motility of the FEI outline along the uterine axis in the sagittal cross section, and there by the related dynamics characteristics. Furthermore, modification of the processing methodology enabled the analysis of the motility of the EMI outline, and consequently, its dynamic characteristics . More recently, the method of active contours was utilized to detect the contours of the EMI and dynamic analysis of uterine peristalsis was conducted data acquired from control and post‐Cesarean section subjects .…”

Section: Uterine Peristalsismentioning

confidence: 99%

See 1 more Smart Citation

Biomechanics of the human uterus

Myers

Elad

2017

WIREs Mechanisms of Disease

View full text Add to dashboard Cite

The appropriate biomechanical function of the uterus is required for the execution of human reproduction. These functions range from aiding the transport of the embryo to the implantation site, to remodeling its tissue walls to host the placenta, to protecting the fetus during gestation, to contracting forcefully for a safe parturition and postpartum, to remodeling back to its nonpregnant condition to renew the cycle of menstruation. To serve these remarkably diverse functions, the uterus is optimally geared with evolving and contractile muscle and tissue layers that are cued by chemical, hormonal, electrical, and mechanical signals. The relationship between these highly active biological signaling mechanisms and uterine biomechanical function is not completely understood for normal reproductive processes and pathological conditions such as adenomyosis, endometriosis, infertility and preterm labor. Animal studies have illuminated the rich structural function of the uterus, particularly in pregnancy. In humans, medical imaging techniques in ultrasound and magnetic resonance have been combined with computational engineering techniques to characterize the uterus in vivo, and advanced experimental techniques have explored uterine function using ex vivo tissue samples. The collective evidence presented in this review gives an overall perspective on uterine biomechanics related to both its nonpregnant and pregnant function, highlighting open research topics in the field. Additionally, uterine disease and infertility are discussed in the context of tissue injury and repair processes and the role of computational modeling in uncovering etiologies of disease. WIREs Syst Biol Med 2017, 9:e1388. doi: 10.1002/wsbm.1388 For further resources related to this article, please visit the WIREs website.

show abstract

A new method for analysis of non‐pregnant uterine peristalsis using transvaginal ultrasound

Abstract: Objectives To develop an objective method for analysis of uterine peristalsis using transvaginal sonography (TVS). Methods

Cited by 22 publications

References 15 publications

Quantitative imaging of tongue kinematics during infant feeding and adult swallowing reveals highly conserved patterns

Quantitative imaging of tongue kinematics during infant feeding and adult swallowing reveals highly conserved patterns

Dynamic Changes in the Myometrium during the Third Stage of Labor, Evaluated Using Two-Dimensional Ultrasound, in Women with Normal and Abnormal Third Stage of Labor and in Women with Obstetric Complications

Biomechanics of the human uterus

Contact Info

Product

Resources

About