A new molecular imprinting‐based mass‐sensitive sensor for real‐time detection of 17β‐estradiol from aqueous solution

Özgür, Erdoğan; Yılmaz, Erkut; Şener, Gülsu; Uzun, Lokman; Say, Rıdvan; Deni̇zli̇, Adil

doi:10.1002/ep.11718

Cited by 29 publications

(10 citation statements)

References 32 publications

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“…A number of reports focused on the synthesis of polymers via imprinting applied for aminoacids [20], peptides [21], carbohydrates [22], nucleotides [23], hormones [24], drugs [25], toxins [26], pesticides [27]. …”

Section: Use Of Molecularly Imprinted Polymers In Affinity Recognimentioning

confidence: 99%

Imprinting of Microorganisms for Biosensor Applications

İdil

Mattìasson

2017

Sensors

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There is a growing need for selective recognition of microorganisms in complex samples due to the rapidly emerging importance of detecting them in various matrices. Most of the conventional methods used to identify microorganisms are time-consuming, laborious and expensive. In recent years, many efforts have been put forth to develop alternative methods for the detection of microorganisms. These methods include use of various components such as silica nanoparticles, microfluidics, liquid crystals, carbon nanotubes which could be integrated with sensor technology in order to detect microorganisms. In many of these publications antibodies were used as recognition elements by means of specific interactions between the target cell and the binding site of the antibody for the purpose of cell recognition and detection. Even though natural antibodies have high selectivity and sensitivity, they have limited stability and tend to denature in conditions outside the physiological range. Among different approaches, biomimetic materials having superior properties have been used in creating artificial systems. Molecular imprinting is a well suited technique serving the purpose to develop highly selective sensing devices. Molecularly imprinted polymers defined as artificial recognition elements are of growing interest for applications in several sectors of life science involving the investigations on detecting molecules of specific interest. These polymers have attractive properties such as high bio-recognition capability, mechanical and chemical stability, easy preparation and low cost which make them superior over natural recognition reagents. This review summarizes the recent advances in the detection and quantification of microorganisms by emphasizing the molecular imprinting technology and its applications in the development of sensor strategies.

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Section: Use Of Molecularly Imprinted Polymers In Affinity Recognimentioning

confidence: 99%

Imprinting of Microorganisms for Biosensor Applications

İdil

Mattìasson

2017

Sensors

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“…Forensic analysis approaches are also applicable for anti-doping purposes to determine doping with performance-enhancing drugs, stimulants, steroids, and corticosteroids [26,27,28,29,30]. Ozgur et al developed a mass sensitive sensor for real time estradiol detection.…”

Section: Imprinting Approaches For Forensic Sciencementioning

confidence: 99%

“…They synthesized MIP nanoparticles and used them as recognition elements on quartz crystals. They reported that the resulting nanosensor had a high selectivity and sensitivity against target molecules in the concentration range of 3.67 nM–3.67 pM and the LOD and LOQ values they calculated were quite low, at 613 fM and 2.04 pM, respectively [27]. Zulfiqar et al developed a MIP-SPE system for extracting and screening multiple steroids in urine.…”

Section: Imprinting Approaches For Forensic Sciencementioning

confidence: 99%

Molecular Imprinting Applications in Forensic Science

Yılmaz

Gari̇pcan

Uzun

2017

Sensors

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Producing molecular imprinting-based materials has received increasing attention due to recognition selectivity, stability, cast effectiveness, and ease of production in various forms for a wide range of applications. The molecular imprinting technique has a variety of applications in the areas of the food industry, environmental monitoring, and medicine for diverse purposes like sample pretreatment, sensing, and separation/purification. A versatile usage, stability and recognition capabilities also make them perfect candidates for use in forensic sciences. Forensic science is a demanding area and there is a growing interest in molecularly imprinted polymers (MIPs) in this field. In this review, recent molecular imprinting applications in the related areas of forensic sciences are discussed while considering the literature of last two decades. Not only direct forensic applications but also studies of possible forensic value were taken into account like illicit drugs, banned sport drugs, effective toxins and chemical warfare agents in a review of over 100 articles. The literature was classified according to targets, material shapes, production strategies, detection method, and instrumentation. We aimed to summarize the current applications of MIPs in forensic science and put forth a projection of their potential uses as promising alternatives for benchmark competitors.

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“…The quantification and limit of detection were 2.04 pM and 613 fM, respectively. The proposed imprinted QCM sensor [ 75 ] had a good long-lasting storage stability, resistance to microbial growth, robustness and reusability and, therefore, was cost effective. In a related study, mass-sensitive detection of folic acid was performed with the help of molecularly imprinted films and nanoparticles.…”

Section: Selected Sensor Applications Of Imprinted Nanomaterialsmentioning

confidence: 99%

Molecularly Imprinted Nanomaterials for Sensor Applications

et al. 2013

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Molecular imprinting is a well-established technology to mimic antibody-antigen interaction in a synthetic platform. Molecularly imprinted polymers and nanomaterials usually possess outstanding recognition capabilities. Imprinted nanostructured materials are characterized by their small sizes, large reactive surface area and, most importantly, with rapid and specific analysis of analytes due to the formation of template driven recognition cavities within the matrix. The excellent recognition and selectivity offered by this class of materials towards a target analyte have found applications in many areas, such as separation science, analysis of organic pollutants in water, environmental analysis of trace gases, chemical or biological sensors, biochemical assays, fabricating artificial receptors, nanotechnology, etc. We present here a concise overview and recent developments in nanostructured imprinted materials with respect to various sensor systems, e.g., electrochemical, optical and mass sensitive, etc. Finally, in light of recent studies, we conclude the article with future perspectives and foreseen applications of imprinted nanomaterials in chemical sensors.

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A new molecular imprinting‐based mass‐sensitive sensor for real‐time detection of 17β‐estradiol from aqueous solution

Cited by 29 publications

References 32 publications

Imprinting of Microorganisms for Biosensor Applications

Imprinting of Microorganisms for Biosensor Applications

Molecular Imprinting Applications in Forensic Science

Molecularly Imprinted Nanomaterials for Sensor Applications

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