A New Monoterpene Alkaloid From the Stems of Rauvolfia vomitoria

Zhan, Guanqun; Yang, Kailing; Yang, Tao; Li, Xiaolei; Zhou, Ruixi; Miao, Rongkun; Guan, Yuyan; Teng, Yanguo; Guo, Zengjun

doi:10.25135/rnp.353.2204.2432

Cited by 1 publication

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“…(R)-10-hydroxyl-4-noractinidine (3) was extracted and isolated from Rauvolfia vomitoria's trunk, the first reported monoterpene alkaloid in R. vomitoria (Apocynaceae) [17].…”

Section: Classes Of Terpenoidal Alkaloids 21 Monoterpenoid Alkaloidsmentioning

confidence: 99%

“…Caryopterisines F-I (4-7) and caryopterisines C-E (16)(17)(18) were subsequently isolated from C. glutinosa Rehder. Caryopterisines F-I (4-7) are four monoterpene alkaloids containing the cyclopentyl[c]pyridine skeleton, while caryopterisines C-E (16-18) represent three novel dimeric monoterpene alkaloids and are believed to be biosynthesized via the Diels-Alder reaction followed by aromatization rearrangement and a series of subsequent reactions [23].…”

Section: Classes Of Terpenoidal Alkaloids 21 Monoterpenoid Alkaloidsmentioning

confidence: 99%

“…Caryopterisines F-I (4-7) are four monoterpene alkaloids containing the cyclopentyl[c]pyridine skeleton, while caryopterisines C-E (16-18) represent three novel dimeric monoterpene alkaloids and are believed to be biosynthesized via the Diels-Alder reaction followed by aromatization rearrangement and a series of subsequent reactions [23]. Of these, caryopterisine C ( 16) has an unprecedented 6/5/6/6/5 pentacyclic ring framework, while caryopterisines D (17) and E (18) both have 6/6/6/5 fused ring frameworks.…”

Section: Classes Of Terpenoidal Alkaloids 21 Monoterpenoid Alkaloidsmentioning

confidence: 99%

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Exploring the Biomedical Potential of Terpenoid Alkaloids: Sources, Structures, and Activities

Wang,

Xin,

Sun

et al. 2024

Molecules

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Terpenoid alkaloids are recognized as a class of compounds with limited numbers but potent biological activities, primarily derived from plants, with a minor proportion originating from animals and microorganisms. These alkaloids are synthesized from the same prenyl unit that forms the terpene skeleton, with the nitrogen atom introduced through β-aminoethanol, ethylamine, or methylamine, leading to a range of complex and diverse structures. Based on their skeleton type, they can be categorized into monoterpenes, sesquiterpenes, diterpenes, and triterpene alkaloids. To date, 289 natural terpenoid alkaloids, excluding triterpene alkaloids, have been identified in studies published between 2019 and 2024. These compounds demonstrate a spectrum of biological activities, including anti-inflammatory, antitumor, antibacterial, analgesic, and cardioprotective effects, making them promising candidates for further development. This review provides an overview of the sources, chemical structures, and biological activities of natural terpenoid alkaloids, serving as a reference for future research and applications in this area.

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“…(R)-10-hydroxyl-4-noractinidine (3) was extracted and isolated from Rauvolfia vomitoria's trunk, the first reported monoterpene alkaloid in R. vomitoria (Apocynaceae) [17].…”

Section: Classes Of Terpenoidal Alkaloids 21 Monoterpenoid Alkaloidsmentioning

confidence: 99%

Section: Classes Of Terpenoidal Alkaloids 21 Monoterpenoid Alkaloidsmentioning

confidence: 99%

Section: Classes Of Terpenoidal Alkaloids 21 Monoterpenoid Alkaloidsmentioning

confidence: 99%

See 1 more Smart Citation

Exploring the Biomedical Potential of Terpenoid Alkaloids: Sources, Structures, and Activities

Wang,

Xin,

Sun

et al. 2024

Molecules

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A New Monoterpene Alkaloid From the Stems of Rauvolfia vomitoria

Cited by 1 publication

References 0 publications

Exploring the Biomedical Potential of Terpenoid Alkaloids: Sources, Structures, and Activities

Exploring the Biomedical Potential of Terpenoid Alkaloids: Sources, Structures, and Activities

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