This article presents research about a hybrid power system dedicated to Internet of Things (IoT) nodes. As an introduction, performance tests of the harvesters, that is, a 40 × 40 mm Peltier cell based on Bi2Te3 and three solar cells, monocrystalline, polycrystalline, and amorphous, are presented. The study established the dependence of the effect of generated power on the load resistance. Thus, it states how the internal resistance of the harvesters changes. Following the above tests, a complete power unit with a single harvester and an LTC3108 conversion circuit, as well as an energy buffer in the form of a 1 mF supercapacitor, were built and tested. The unit with a thermoelectric generator generated power from 14 to 409 µW. The unit with a 65 × 65 mm polycrystalline cell generated power from 150 to 409 µW. Next, a hybrid system was built and tested with both of the aforementioned harvesters, which generated power from 205 to 450 µW at 2000 lx illumination and a temperature difference of 20 °C for the thermoelectric generator claddings.