A New Pd⁰���Cu^IBimetallic Catalyst for the Synthesis of Indoles from Isocyanates and Allyl Carbonates

Abstract

In the research field of transition-metal-catalyzed organic synthesis, one of the modern trends is to use a bimetallic catalyst system to explore not only more efficient but also entirely new transformations. Representative examples of such bimetallic catalysis in palladium-catalyzed reactions [1] are the following: 1) cat.Pd 0 /Cu I in the Sonogashira coupling reaction, in which a catalytic amount of Cu salts activate terminal acetylenes to form copper±acetylide species; [2] 2) cat Pd 0 /Cu I in the Stille coupling reaction, in which organostannanes are transmetalated to give organocoppers which ZUSCHRIFTEN 3364