2020
DOI: 10.21203/rs.3.rs-89273/v1
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A New Perspective on Calmodulin Regulated Calcium and Ros Homeostasis Upon Carbon Black Nanoparticle Exposure

Abstract: BackgroundToxicological studies propose that exposure to carbon black nanoparticles induces organ injuries and inflammatory responses. Besides, current understanding of the molecular mechanisms implies that carbon black nanoparticles (CBNP) exposure induces the production of reactive oxygen species (ROS) causing inflammation, mitochondrial dysfunction, or disturbance in calcium homeostasis. However, the precise mechanisms whereby CBNP exert these effects in the lung are still not fully understood. To gain insi… Show more

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