A new phenanthro [2,3-b] furan from Pleione bulbocodioides

Chemical Constituents and Biological Activity Profiles on Pleione (Orchidaceae)

“…The compounds such as 26 , 34 , 44 , 58 , 60 and 153 were demonstrated certain inhibitory effects against LA795 at 100 μg·mL −1 . Liu [37] confirmed that 34 and 153 showed the cytotoxic activity against LA795 cells with IC 50 value of 66 and 12 μg·mL −1 . Compound 58 exhibited cytotoxic activity and anti-allergic activity.…”

“…Among those activities, that against tumors was the most significant. Liu [37] proved that the ethyl acetate extract of P. bulbocodiodes had a certain inhibitory effect on mice cancer cells LA795, while the petroleum ether extract only had an inhibition rate of 75.58% at 800 μg·mL −1 , but no remarkable inhibition at 400 μg·mL −1 and below. However, the n -butanol extract did not exert inhibitory at all.…”

Chemical Constituents from the Aerial Parts of Cyrtopodium paniculatum

“…The connection between the two units allows a new cyclization leading to a furan ring. It is noteworthy that this kind of dihydrophenanthrene derivative is considered as a chemotaxonomic marker for the species in the genus Pleione [59,73,[75][76][77], but has been also found in the genus Bulbophyllum [55] and Cremastra [54]. The last set of compounds were the dimers, occurring as either homo-(two units of 9,10-dihydrophenanthrene or phenanthrene) or as heterodimers (combinations of a 9,10-dihydrophenanthrene and a phenanthrene unit) having a C-C bond linkage.…”

Rare and Precious Chinese Materia Medica: Pseudobulbus Cremastrae seu Pleiones

“…[20] This was the first report of the isolation of biphenanthrene atropisomers (33 and 34) from the plant kingdom. (42), physcion (43), chrysophanol (44), emodin (45), genkwanin (46), quercetin (47), quercetin 3'-O-b-D-glucopyranoside (48), 3-methoxy-4-hydroxy phenylethanol (49), syringic acid (50), and vanillin (51). [21] Seven known phenanthrenes were isolated from an ethanolic extract and identified as 2,7,7′-trihydroxy-4,4′-dimethoxy-9′,10′-dihydro-1,2′biphenanthreneether (blestrin C, 52), 2,7,7′-trihydroxy-4,5′dimethoxy-9′,10′-dihydro-1,2′-biphenanthreneether (blestrin D, 53), 4,7,4′-trimethoxy-9′,10′-dihydro-(1,1′-biphenanthrene)-2,2′,7′-triol (54), phochinenin B (55), 2,7,2′-trihydroxy-4,4′,7′-tr imethoxy-1,1′-biphenanthrene (56), 2,2′-dihydroxy-4,4′,7,7′t e t r a m e t h o x y -1 , 1 ′ -b i p h e n a n t h r e n e ( 5 7 ) , [ 1 8 ] a n d 1-(4′-hydroxybenzyl)-4-methoxyphenanthrene-2,7diol (58).…”