A New Regimen of Complex Therapy for Aggressive Periodontitis

Abstract

The aim of the investigation was to evaluate the efficacy of the new regimen of complex therapy for rapidly progressing periodontitis with the use of medications affecting bone tissue restoration and remodeling. Materials and Methods. Treatment results were analyzed in 45 patients diagnosed with rapidly progressing periodontitis. The control group consisted of 12 practically healthy individuals. Metronidazole suspension was introduced into the periodontal pockets of patients in group 1, while patients of group 2 underwent introduction of Metronidazole and Aplun mixture in suspension. General treatment in both groups included administration of Tevabone. In patients of group 3, Metronidazole suspension was introduced in the periodontal pockets, while general treatment included the use of Calcemin. Results. Clinical studies and biochemical parameters of the oral fluid in patients of group 2 evidenced rapid and sustained decrease in inflammation, earlier regeneration of the periodontal tissue and bone restoration as compared to groups 1 and 3. Conclusion. The proposed regimen of complex therapy for rapidly progressing periodontitis including locally used Aplun medication in addition to administration of Tevabone has demonstrated greater treatment efficacy as compared to conventional therapy.

The Effect of Intra-Pocket Application of Diode Laser on the Mobility of Teeth With Grade C Periodontitis

“…Other authors used metronidazole tablets and drops of liquid aplun (a complex compound of lanthanum nitrate and tri-ethylene glycol in glycerol) complexed with teva bone applied inside the periodontal pocket in rapidly progressing periodontitis. The results revealed a marked decrease in tooth mobility following the 30 days of treatment, this was in agreement with our study although they used different complex of medications which may be attributed to antiinflammatory and antimicrobial activity (40).…”

“…They advocated the use of diode lasers to prevent bacteremia. A 980 nm diode laser has been also used to reduce periodontal pathogenic bacteria in aggressive periodontitis patients (40). Kamma et al have proven that the total bacterial load in pockets could be reduced by applying laser therapy without the use of systemic antibiotic therapy (16).…”

The State of Antioxidant Systems and Lipids’ Peroxidation Under the Action of Complex Substances

“…Lanthanum compounds reduce accumulation of calcium in the skin that positively affects its elasticity and prevents the appearance of wrinkles. In addition, lanthanide ions have an affinity for phospholipids that helps to stabilize the cell membrane by blocking of ion channels [12].…”