A new resveratrol octamer, vateriaphenol A, in Vateria indica

Chemical Constituents in the Leaves of Vateria indica

“…14) As discussed in previous articles, the behavior of some protons in stilbene oligomers is very complicated. 3,4,[22][23][24][25] Therefore, further spectroscopic evidence in connection with steric factors are required for the accurate determination of the configuration in stilbene oligomers such as 1 and related compounds.…”

“…[2][3][4][5][6] Our previous study demonstrated that the leaves also contain stilbene derivatives in high quantity. 6) Recently, the bioactivities of stilbenoids isolated from Dipterocarpaceaeous plants have been reported to have antimicrobial activites, 7,8) antitumor activities, [9][10][11] and regulation of endoplasmic reticulum stress.…”

“…The various structures are dependent upon the skeletal variation and the stereoisomers. Comprehensive investigation of the chemical constituents in the leaves of V. indica resulted in the isolation and characterization of a new resveratrol tetramer [vateriaphenol F (1)] and two new O-glucosides of resveratrol oligomers [vateriosides A (2) and B (4)], along with a new natural compound (3), and 33 known compounds [resveratrol derivatives , flavonols (31)(32)(33), diterpenes (34,35), an isocoumarin (36), and a phenylpropanoid (37)]. The structures of the new compounds (1, 2, 4) were elucidated by 2D NMR techniques such as 1 H-1 H correlation spectroscopy (COSY), 13 C-1 H COSY, and heteronuclear multiple bond connectivity (HMBC).…”

Occurrence of C-Glucoside of Resveratrol Oligomers in Hopea parviflora

“…Our previous phytochemical study demonstrated that the structural diversity is due to the oligomerization degree of the blocking unit of resveratrol, which generates a skeletal variation and complicated stereostructures, and the production of O-and C-glucosides. [1][2][3][4][5][6][7][8][9][10][11][12][13][14] The genus Hopea belongs to Shoreae, one of the two major tribes of the subfamily Dipterocarpoideae, with about 102 species distributed throughout southeast Asia, especially in Indonesia and Malaysia, southern China, southern and eastern India, and Sri Lanka. 15) During this decade, this genus has been well documented to be a good source of biologically active stilbenoids.…”

“…In the current study, we focused on the highly polar components present in this tribe and reinvestigated the methanol extract of the stem of H. parviflora. This study reports the isolation of four new stilbene glucosides [hopeasides A (1)-D (4)] along with nine known compounds (5)(6)(7)(8)(9)(10)(11)(12)(13). Their structures were elucidated by extensive spectroscopic methods, including 1D-and 2D-NMR experiments and high-resolution electron spray ionization mass spectra (HR-ESI-MS) analysis, and clarified by computer-aided molecular modeling.…”