A new sensor based on thieno[2,3‐b]quinoline for the detection of In³⁺, Fe³⁺ and F⁻ by different fluorescence behaviour

Abstract

Based on thieno[2,3‐b]quinoline‐2‐carbohydrazide and salicylaldehyde, a novel fluorescent probe (L) was designed and synthesized. L could be used as a multifunctional sensor to sequentially detect In3+ and Fe3+ through fluorescence enhancement and fluorescence quenching in DMF/H2O buffer solutions. At the same time, L had good anti‐interference ability, which could still detect In3+ and Fe3+ well in the presence of other metal ions. For F−, it could be detected by enhancing the fluorescence change caused by the introduction of Al3+. When other anions were present, the detection of F− would not be interfered. The detection limits of In3+, Fe3+ and F− were 1.16 × 10−10 M, 2.03 × 10−8 M and 7.98 × 10−9 M, respectively. The complexation model and sensing mechanism between L and In3+, Fe3+ and F− were confirmed by calculating structural optimization and energy optimization using Gaussian 09 software.

Increased Free Radical Generation during the Interaction of a Quinone-Quinoline Chelator with Metal Ions and the Enhancing Effect of Light

“…Quinoline and its derivatives have wide biological and pharmacological applications, including anticancer and antimicrobial activity [31][32][33][34][35][36][37][38][39][40]. Similar diverse activity has also been shown by transition and other metal complexes of quinoline and its derivatives, such as 8-hydroxyquinoline (Figure 1) [41][42][43][44][45][46][47][48][49][50]. In contrast, quinones with redox properties similar to Q1, but without a chelating center, have shown much less cytotoxic activity toward cancer cells [5].…”

A colorimetric, NIR, ultrafast fluorescent probe for ferric iron detection based on the PET mechanism and its multiple applications

“…10,20 Most of these fluorescent probes are of ''turn-off'' responding mode, which is mainly because Fe 3+ (d-block ions) can easily open excited state deexcitation pathways involving the metal centre via photoinduced electron transfer (PET) or electronic energy transfer (EET). [21][22][23] However, it is worth noting that the near-infrared (NIR) emission probes of turn off or turn on modes for recognition of Fe 3+ are still few.…”