A New Sesquiterpene from Trichilia casarettii (Meliaceae)

Abstract

The dichloromethane extract of the air-dried stems of Trichilia casarettii afforded a new sesquiterpene (1), lupeol, stigmasterol, campesterol and sitosterol. The structure of 1 was elucidated by extensive one-and twodimensional nuclear magnetic resonance and mass spectrometry.

Two Novel Cycloartane-Type Triterpenes from Trichilia casaretti C. DC. (Meliaceae)

“…The Meliaceae family has attracted such a great interest among phytochemists because of its relatively complex and diverse chemical structures and its biological activity, mainly against insects [ 1 , 2 , 3 , 4 ]. The Trichilia genus (Meliaceae) comprises about 230 species distributed throughout tropical America, which are recognized for their significant economic importance and high commercial value.…”

“…The Trichilia genus (Meliaceae) comprises about 230 species distributed throughout tropical America, which are recognized for their significant economic importance and high commercial value. Phytochemical studies revealed that this genus is a potential source of terpenoids, including triterpenes, limonoids, steroids and other terpenes derivatives [ 3 , 4 , 5 , 6 ]. Species of this genus have been also studied for their insecticidal activities and their isolated compounds revealed complex and interesting structures including various limonoids [ 5 , 7 , 8 ].…”

“…Species of this genus have been also studied for their insecticidal activities and their isolated compounds revealed complex and interesting structures including various limonoids [ 5 , 7 , 8 ]. The isolation and structural elucidation of two novel sesquiterpenes from the stems of T. casaretti collected in Espírito Santo State, Brazil, were reported by Vieira et al in 2010 [ 4 ].…”

Hirtinone, a Novel Cycloartane-Type Triterpene and Other Compounds from Trichilia hirta L. (Meliaceae)

“…The Meliaceae family has attracted such a great interest among phytochemists interested in bioproduction because of its very complex and diverse chemical structures and its biological activity, mainly against insects [1,2,3,4]. The Trichilia genus (Meliaceae) consists of about 230 species distributed throughout tropical America, which are recognized for their significant economic importance and high commercial value.…”

Lepidotrichilins A and B, New Protolimonoids with Cytotoxic Activity from Trichilia Lepidota (Meliaceae)

“…This wood of this species is used to make furniture [1]. The Trichilia genus consists of about 230 species distributed throughout tropical America and other countries ranging from Africa and Asia [2,3]. Previous investigations on the chemical constituents of the dichloromethane extract from the leaves of this species revealed the presence of hydrocarbons mixtures (C 29 H 60 , C 31 H 64 and C 33 H 68 ), sesquiterpenes, steroids, amino acids and other compounds derived from the terpene metabolic pathway [4].…”