Based on the Roesser model with saturation nonlinearities (SNL) and time-varying delays (TVDs), this paper studies the global asymptotic stability (GAS) of two-dimensional (2-D) uncertain discrete systems (DSs). The underlying system involves norm-bounded parameter uncertainties. By utilizing the idea of Wirtinger-based inequality (WBI) with reciprocal convex inequality (RCI), a new criterion is derived to ensure the GAS of 2-D systems. Numerical examples demonstrate the advantages of the proposed method.With the MATLAB software and YALMIP 3.0, it is found that the obtained criterion provides less stringent results than an existing criterion.