Proceedings of the 24th International Electronic Conference on Synthetic Organic Chemistry 2020
DOI: 10.3390/ecsoc-24-08403
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A new synthesis of 3-arylideneamino- and 3-alkylideneamino-substituted hydantoins

Abstract: A novel straightforward approach to 3-arylideneamino-and 3-alkylideneaminohydantoins has been developed. It is based on reaction of readily available 4-(tosylmethyl)semicarbazones with NaCN in DMF followed by heating of the obtained α-(4semicarbazono)nitriles with conc. HCl.

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