A New Synthetic Method for Controlled Polymerization Using a Microfluidic System

Abstract

Polymer materials applications increasingly show sensitivity to single-chain variables such as molecular mass and copolymer composition. [1][2][3] While many parallel synthesis methods developed by the pharmaceutical and life science communities are being applied to polymer synthesis, 4,5 there remains a need to construct polymeric material "libraries" that explore a wide range of polymer structures with accuracy, flexibility, and rapid, often precise, changes.Recent development of various analytical methods, such as micrototal analytical systems (µTAS), 6,7 have also increased the

Microfluidics-Nano-Integration for Synthesis and Sensing

“…Most of the work on the microfluidic synthesis of linear polymers was done by radical polymerization or copolymerization, initiated by thermal or photoinitiators [35]. The authors (Wu et al) demonstrated the effect of the flow rate-that is the polymerization time-on the molecular mass of the polymer.…”

Microfluidic Approach for the Synthesis of Micro- or Nanosized Molecularly Imprinted Polymer Particles

“…For high performance, development of new materials and novel fabrication techniques has been actively studied in this area. Synthesis of new materials for nanoimprinting lithography, soft lithography, microfluidic technique, and plastic electronics is of interest for chemists to expand the scope of current nanotechnology to advanced levels [1][2][3][4][5][6][7][8][9][10][11].…”

“…Microfluidic reactors have been designed then used for synthesis of both organics and inorganics. Recently several groups have reported microfluidic strategies for the synthesis of organic and inorganic materials [8][9][10][11].…”

“…For example, Beers et al has demonstrated a high-yield photopolymerization occurred in the micro-fluidic reactor by taking an advantage of its low oxygen permeability [8]. Kobayashi designed several microfluidic reactors for multiphase reactions to achieve effective interactions between the multiple components [9].…”

Polimerização em solução desenvolvida em milireatores.

“…Concerning back mixing, the introduction of a dimensionless number can be useful in order to represent the ratio between the axial dispersion time and the mean residence time, called the Bodenstein number: (65) with axial dispersion (correlated to molecular diffusion, as eq. (66) will show) and mean residence time.…”