A new technique for simultaneous validation of two manual nonmercury auscultatory sphygmomanometers (A&amp;D UM-101 and Accoson Greenlight 300) based on the International protocol

Pruijm, Menno; Wuerzner, Grégoire; Glatz, Nicolas; Alwan, Heba; Ponte, Belén; Ackermann, Daniel; Burnier, Michel; Bochud, Murielle

doi:10.1097/mbp.0b013e32833f56a8

Cited by 15 publications

(14 citation statements)

References 6 publications

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“…6 This decision is justified by the results of two recent validation studies of electronic auscultatory devices 14 that used the ESH-IP, but with simultaneous measurements and reported similar findings as in validation studies of the same devices using the ESH-IP with sequential measurements. 15,16 The accuracy of at least four mercury-free electronic auscultatory devices has been tested using the ESH-IP protocol, using sequential [15][16][17][18] or simultaneous measurements.…”

Section: Professional Blood Pressure Monitor Gs Stergiou Et Almentioning

confidence: 97%

“…15,16 The accuracy of at least four mercury-free electronic auscultatory devices has been tested using the ESH-IP protocol, using sequential [15][16][17][18] or simultaneous measurements. 14 The Accoson Greenlight device (Accoson Works, Harlow Business Park, Harlow, Essex, UK), which has a LED scale display similar to an aneroid device, was shown to have 84 of the systolic and 74 of the diastolic BP measurements (out of 99) within 5 mm Hg from those obtained by a mercury sphygmomanometer using sequential measurements, 15 and 81 and 87, respectively, using simultaneous measurements. 14 The A&D UM101 hybrid device (A&D Company, Ltd., Toshima Ku, Tokyo, Japan), which has a liquid crystal display column very similar to that of the device tested in this study, had 87/91 of 99 systolic/diastolic measurements within 5 mm Hg from the mercury device using sequential measurements, 16 and 86/94, respectively, using simultaneous measurements.…”

Section: Professional Blood Pressure Monitor Gs Stergiou Et Almentioning

confidence: 99%

“…14 The Accoson Greenlight device (Accoson Works, Harlow Business Park, Harlow, Essex, UK), which has a LED scale display similar to an aneroid device, was shown to have 84 of the systolic and 74 of the diastolic BP measurements (out of 99) within 5 mm Hg from those obtained by a mercury sphygmomanometer using sequential measurements, 15 and 81 and 87, respectively, using simultaneous measurements. 14 The A&D UM101 hybrid device (A&D Company, Ltd., Toshima Ku, Tokyo, Japan), which has a liquid crystal display column very similar to that of the device tested in this study, had 87/91 of 99 systolic/diastolic measurements within 5 mm Hg from the mercury device using sequential measurements, 16 and 86/94, respectively, using simultaneous measurements. 14 Another hybrid device of similar design (Pic Indolor Professional, Artsana Co., Milan, Italy) gave excellent results with 98 of 99 systolic BP measurements and all 99 diastolic measurements differing p5 mm Hg from the mercury sphygmomanometer.…”

Section: Professional Blood Pressure Monitor Gs Stergiou Et Almentioning

confidence: 99%

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A perfect replacement for the mercury sphygmomanometer: the case of the hybrid blood pressure monitor

et al. 2011

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This study validated a hybrid mercury-free device as a replacement of the mercury sphygmomanometer for professional use, and also as a standard for future validations. A validation study was performed according to the European Society of Hypertension International Protocol 2010 (ESH-IP) in 33 subjects using simultaneous blood pressure (BP) measurements. A total of six BP measurements were taken per participant simultaneously by a supervisor (S; hybrid auscultatory device Nissei DM3000) and two observers (A and B; mercury sphygmomanometers). ESH-IP analysis (99 BP readings): mean device-observer systolic/diastolic BP difference 0.2±2.0/0.1±2.0 mm Hg; systolic BP differences p5/10/15 mm Hg in 97/99/99 readings, respectively (diastolic 98/99/99). All 33 subjects had 2 of 3 BP differences p5 mm Hg and none without a difference p5 mm Hg. Further analysis (198 BP readings): mean differences S-A 0.1 ± 2.4/0.2 ± 2.4 mm Hg (systolic/diastolic), S-B 0.3 ± 2.1/0.2 ± 2.2, A-B 0.2 ± 2.4/0.0 ± 2.3; differences p2 mm Hg S-A in 88/84% (systolic/diastolic), S-B 87/85%, A-B 87/86% and p4 mm Hg S-A 95/ 96%, S-B 95/96%, A-B 95/98%. In conclusion, a hybrid mercury-free auscultatory BP monitor comfortably passed the ESH-IP 2010 requirements and has the same level of accuracy as the mercury sphygmomanometer. This device appears to be a reliable alternative to the mercury sphygmomanometer for professional use and also as a standard for future validations.

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Section: Professional Blood Pressure Monitor Gs Stergiou Et Almentioning

confidence: 97%

Section: Professional Blood Pressure Monitor Gs Stergiou Et Almentioning

confidence: 99%

Section: Professional Blood Pressure Monitor Gs Stergiou Et Almentioning

confidence: 99%

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A perfect replacement for the mercury sphygmomanometer: the case of the hybrid blood pressure monitor

et al. 2011

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“…BP was measured 5 times in clinic after a resting period of at least 10 minutes in the sitting position with an appropriately sized arm cuff and a nonmercury manual auscultatory sphygmomanometer (A&D UM-101; A&D Company Ltd, Toshima Ku, Tokyo, Japan), 18 according to the guidelines of the European Society of Hypertension. BP and heart rate were the mean of 4 measurements before the recording of PWV.…”

Section: Study Visits and Definitionsmentioning

confidence: 99%

Inactive Matrix Gla-Protein Is Associated With Arterial Stiffness in an Adult Population–Based Study

et al. 2015

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Increased pulse wave velocity (PWV) is the gold standard in assessing stiffening of the aorta.1 As shown by 3 population studies, all including over thousand participants, PWV refines risk stratification above and beyond traditional cardiovascular risk factors. In multivariable-adjusted analyses, per one standard deviation (SD) increment in PWV, cardiovascular mortality increased by 20% and 60% in a Danish and Taiwanese population samples, respectively.2,3 The Framingham heart study found that one standard deviation increment of PWV was associated with a 48% increase in cardiovascular disease risk. 4 Matrix Gla-protein (MGP) is acting as a strong inhibitor of soft tissue calcification. 5,6 MGP knockout mice develop massive vascular calcification in their first weeks of life and die within 2 months of vessels rupture.7 MGP is expressed primarily by chondrocytes and vascular smooth muscle cells. 8,9 To acquire its full calcification inhibitory activity, MGP needs to undergo 2 post-translational modifications: glutamate carboxylation and serine phosphorylation. Both modifications are not exerted completely, so theoretically, 4 different MGP conformations can be found: unmodified and Abstract-Increased pulse wave velocity (PWV) is a marker of aortic stiffness and an independent predictor of mortality.Matrix Gla-protein (MGP) is a vascular calcification inhibitor that needs vitamin K to be activated. Inactive MGP, known as desphospho-uncarboxylated MGP (dp-ucMGP), can be measured in plasma and has been associated with various cardiovascular markers, cardiovascular outcomes, and mortality. In this study, we hypothesized that high levels of dp-ucMGP are associated with increased PWV. We recruited participants via a multicenter family-based crosssectional study in Switzerland. Dp-ucMGP was quantified in plasma by sandwich ELISA. Aortic PWV was determined by applanation tonometry using carotid and femoral pulse waveforms. Multiple regression analysis was performed to estimate associations between PWV and dp-ucMGP adjusting for age, renal function, and other cardiovascular risk factors. We included 1001 participants in our analyses (475 men and 526 women). Mean values were 7.87±2.10 m/s for PWV and 0.43±0.20 nmol/L for dp-ucMGP. PWV was positively associated with dp-ucMGP both before and after adjustment for sex, age, body mass index, height, systolic and diastolic blood pressure (BP), heart rate, renal function, low-and high-density lipoprotein, glucose, smoking status, diabetes mellitus, BP and cholesterol lowering drugs, and history of cardiovascular disease (P≤0.01). In conclusion, high levels of dp-ucMGP are independently and positively associated with arterial stiffness after adjustment for common cardiovascular risk factors, renal function, and age. inactive as desphospho-uncarboxylated MGP (dp-ucMGP), only phosphorylated, only carboxylated, and finally fully modified and active as phosphorylated and carboxylated MGP. 10,11 Carboxylation of MGP is a vitamin K-dependent process: vitamin K hydroquinone, a vitamin K m...

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“…This device has passed the International Protocol for validation of BP-measuring devices of the European Society of Hypertension [18] and has been internally validated by our research group [19]. BP was measured after 10 min of rest in the sitting position using both arms.…”

Section: Blood Pressurementioning

confidence: 99%

Heritability of ambulatory and office blood pressure in the Swiss population

Alwan

Ehret²,

Ponte

et al. 2015

Journal of Hypertension

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a Background: Blood pressure (BP) is known to aggregate in families. Yet, heritability estimates are populationspecific and no Swiss data have been published so far. We estimated the heritability of ambulatory and office BP in a Swiss population-based sample. Methods: The Swiss Kidney Project on Genes inHypertension is a population-based family study focusing on BP genetics. Office and ambulatory BP were measured in 1009 individuals from 271 nuclear families. Heritability was estimated for SBP, DBP, and pulse pressure using a maximum likelihood method implanted in the Statistical Analysis in Genetic Epidemiology software. Results:The 518 women and 491 men included in this analysis had a mean (AESD) age of 48.3 (AE17.4) and 47.3 (AE17.7) years, and a mean BMI of 23.8 (AE4.2) and 25.9 (AE4.1) kg/m 2 , respectively. Narrow-sense heritability estimates (AEstandard error) for ambulatory SBP, DBP, and pulse pressure were 0.37 AE 0.07, 0.26 AE 0.07, and 0.29 AE 0.07 for 24-h BP; 0.39 AE 0.07, 0.28 AE 0.07, and 0.27 AE 0.07 for day BP; and 0.25 AE 0.07, 0.20 AE 0.07, and 0.30 AE 0.07 for night BP, respectively (all P < 0.001). Heritability estimates for office SBP, DBP, and pulse pressure were 0.21 AE 0.08, 0.25 AE 0.08, and 0.18 AE 0.07 (all P < 0.01). Conclusions:We found significant heritability estimates for both ambulatory and office BP in this Swiss populationbased study. Our findings justify the ongoing search for the genetic determinants of BP.

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A new technique for simultaneous validation of two manual nonmercury auscultatory sphygmomanometers (A&D UM-101 and Accoson Greenlight 300) based on the International protocol

Abstract: Both the nonmercury devices passed the International protocol. The new technique of simultaneous device testing using a Y-tube represents a time saving application of the International protocol.

Cited by 15 publications

References 6 publications

A perfect replacement for the mercury sphygmomanometer: the case of the hybrid blood pressure monitor

A perfect replacement for the mercury sphygmomanometer: the case of the hybrid blood pressure monitor

Inactive Matrix Gla-Protein Is Associated With Arterial Stiffness in an Adult Population–Based Study

Heritability of ambulatory and office blood pressure in the Swiss population

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