To analyze the kinetic characteristics of a debris flow that occurred on 9 April 2000 in Tibet, China, a meshfree numerical method named smoothed particle hydrodynamics (SPH) is introduced, and two-dimensional and three-dimensional models are established in this work. Based on the numerical simulation, the motion process of this debris flow is reproduced, and the kinetic characteristics are analyzed combining with the field investigation data. In the kinetic analysis, the flow velocity, runout distance, deposition, and energy features are discussed. Simulation results show that the debris flow mass undergoes an acceleration stage after failure, then the kinetic energy gradually dissipates due to the friction and collision during debris flow propagation. Finally, the debris flow mass blocks the Yigong river and forms a huge dam and an extensive barrier lake. The peak velocity is calculated to be about 100 m/s, and the runout distance is approximately 8000 m. The simulation results basically match the data measured in field, thus verifying the good performance of the presented SPH model. This approach can predict hazardous areas and estimate the hazard intensity of catastrophic debris flow.