A new tissue-agnostic microfluidic device to model physiology and disease: the lattice platform

Campo, Hannes; Zha, Didi; Pattarawat, Pawat; Colina, Jose; Zhang, Delong; Murphy, Alina; Yoon, Julia; Russo, Angela; Rogers, Hunter B.; Lee, Hoi Chang; Zhang, Jiyang; Trotter, Katy; Wagner, Sarah; Ingram, Asia; Pavone, Mary Ellen; Dunne, Sara Fernandez; Boots, Christina E.; Urbanek, Margrit; Xiao, Shuo; Burdette, Joanna E.; Woodruff, Teresa K.; Kim, J. Julie

doi:10.1039/d3lc00378g

Lab Chip

2023

DOI: 10.1039/d3lc00378g

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A new tissue-agnostic microfluidic device to model physiology and disease: the lattice platform

Hannes Campo,

Didi Zha,

Pawat Pattarawat

et al.

Abstract: To accurately phenocopy human biology in vitro, researchers have been reducing their dependence on standard, static two-dimensional (2D) cultures and instead are moving towards three-dimensional (3D) and/or multicellular culture techniques....

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Cited by 5 publications

References 52 publications

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Lab Chip

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A 3D-printed multi-compartment organ-on-chip platform with a tubing-free pump models communication with the lymph node

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Organs-on-a-chip to understand reproduction

Kim

2024

Reprod. Fertil. Dev.

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Organs-on-a-chip technology (OoC) has transformed biomedical research with realistic human organ models for drug testing and disease research. While still in its infancy in reproductive research, OoC holds immense potential. The development and use of OoC platforms specifically for reproductive processes are highlighted here, including a multi-organ platform for studying the female reproductive tract, devices for investigating embryo implantation, and microfluidic systems aimed at improving pre-implantation embryos. These findings emphasize the transformative potential of OoC technology in reproductive biology, advocating for its broader adoption in the field. The potential applications of OoC technology in both human and animal reproduction are vast and significant. By providing detailed and controlled models of reproductive systems, OoC technology is set to transform reproductive health research, steering it towards a more sustainable and ethical future.

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Tissue-Engineered Three-Dimensional Platforms for Disease Modeling and Therapeutic Development

Wheeler,

Leach

2024

Tissue Engineering Part B: Reviews

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A new tissue-agnostic microfluidic device to model physiology and disease: the lattice platform

Abstract: To accurately phenocopy human biology in vitro, researchers have been reducing their dependence on standard, static two-dimensional (2D) cultures and instead are moving towards three-dimensional (3D) and/or multicellular culture techniques....

Cited by 5 publications

References 52 publications

A 3D-printed multi-compartment organ-on-chip platform with a tubing-free pump models communication with the lymph node

A 3D-printed multi-compartment organ-on-chip platform with a tubing-free pump models communication with the lymph node

Organs-on-a-chip to understand reproduction

Tissue-Engineered Three-Dimensional Platforms for Disease Modeling and Therapeutic Development

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