It is a well-established fact in regression analysis that multicollinearity and autocorrelated errors have adverse effects on the properties of the least squares estimator. Huang and Yang (2015) and Chandra and Tyagi (2016) studied the PCTP estimator and the − ( , ) class estimator, respectively, to deal with both problems simultaneously and compared their performances with the estimators obtained as their special cases. However, to the best of our knowledge, the performance of both estimators has not been compared so far. Hence, this paper is intended to compare the performance of these two estimators under mean squared error (MSE) matrix criterion. Further, a simulation study is conducted to evaluate superiority of the − ( , ) class estimator over the PCTP estimator by means of percentage relative efficiency. Furthermore, two numerical examples have been given to illustrate the performance of the estimators.