A Newborn With Abdominal Pain

Alwan, Riham; Drake, Meredith; Juarez, Juan Gurria; Emery, Kathleen H.; Shaaban, Aimen F.; Szabo, Sara; Sobolewski, Brad

doi:10.1542/peds.2016-4267

Cited by 4 publications

(2 citation statements)

References 19 publications

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“…With cross‐referencing, eight additional eligible articles were identified. In total, 131 articles were included in this systematic review 3,6,12–140 . Figure 1 provides the PRISMA flowchart.…”

Section: Resultsmentioning

confidence: 99%

Appendicitis and its associated mortality and morbidity in infants up to 3 months of age: A systematic review

The,

Derikx

et al. 2023

Health Science Reports

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Background and AimsAlthough appendicitis is rare in young infants, the reported mortality is high. Primary aim of this systematic review was to provide updated insights in the mortality and morbidity (postoperative complications, Clavien‐Dindo grades I–IV) of appendicitis in infants ≤3 months of age. Secondary aims comprised the evaluation of patient characteristics, diagnostic work‐up, treatment strategies, comorbidity, and factors associated with poor outcome.MethodsThis systematic review was reported according to the PRISMA statement with a search performed in Pubmed, Embase and Web of Science (up to September 5th 2022). Original articles (published in English ≥1980) reporting on infants ≤3 months of age with appendicitis were included. Both patients with abdominal appendicitis and herniated appendicitis (such as Amyand's hernia) were considered. Data were provided descriptively.ResultsIn total, 131 articles were included encompassing 242 cases after identification of 4294 records. Overall, 184 (76%) of the 242 patients had abdominal and 58 (24%) had herniated appendicitis. Two‐hundred (83%) of the patients were newborns (≤28 days) and 42 (17%) were infants between 29 days and ≤3 months of age. Either immediate, or after initial conservative treatment, 236 (98%) patients underwent surgical treatment. Some 168 (69%) patients had perforated appendicitis. Mortality was reported in 20 (8%) patients and morbidity in an additional 18 (8%). All fatal cases had abdominal appendicitis and fatal outcome was relatively more often reported in newborns, term patients, patients with relevant comorbidity, nonperforated appendicitis and those presented from home.ConclusionMortality was reported in 20 (8%) infants ≤3 months of age and additional morbidity in 18 (8%). All patients with fatal outcome had abdominal appendicitis. Several patient characteristics were relatively more often reported in infants with poor outcome and adequate monitoring, early recognition and prompt treatment may favour the outcome.

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Section: Resultsmentioning

confidence: 99%

Appendicitis and its associated mortality and morbidity in infants up to 3 months of age: A systematic review

The,

Derikx

et al. 2023

Health Science Reports

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“…Obstructive etiologies which should be considered include volvulus, Hirschsprung's disease, meconium ileus, or other congenital bowel atresia or obstruction. Infectious etiologies to consider include NEC or a septic ileus [ 20 ]. Spontaneous intestinal perforation may also result in an acute abdomen but occurs in preterm infants.…”

Section: Discussionmentioning

confidence: 99%

Simulation of an Atypical Presentation of Necrotizing Enterocolitis in the Emergency Department

Simpson¹,

Brasher²,

Arnold³

et al. 2021

Cureus

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Necrotizing enterocolitis (NEC) is a gastrointestinal emergency most commonly seen in premature infants, but equally important to recognize in term infants. Early diagnosis and management is critical to achieving optimal patient outcomes. This report outlines a simulation of the challenging scenario of a term infant presenting to the emergency center with NEC as a result of bacteremia and sepsis due to a urinary tract infection (UTI). This simulation can be used for teaching different levels of learners including novice, intermediate, and advanced. It focuses on the presentation, diagnosis, and emergent management of NEC, and additionally incorporates Pediatric Advanced Life Support (PALS) for more advanced learners.

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Neonatal and Infant Appendicitis

Bence

Densmore

2020

Clinics in Perinatology

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A Newborn With Abdominal Pain

Cited by 4 publications

References 19 publications

Appendicitis and its associated mortality and morbidity in infants up to 3 months of age: A systematic review

Appendicitis and its associated mortality and morbidity in infants up to 3 months of age: A systematic review

Simulation of an Atypical Presentation of Necrotizing Enterocolitis in the Emergency Department

Neonatal and Infant Appendicitis

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