A non-enzymatic electrochemical hydrogen peroxide sensor based on copper oxide nanostructures

Abstract

This article describes the synthesis of nanostructured copper oxide on copper wires and its application for the detection of hydrogen peroxide. Copper oxide petal nanostructures were obtained by a one-step hydrothermal oxidation method. The resulting coating is uniform and dense and shows good adhesion to the wire surface. Structure, surface, and composition of the obtained samples were studied using field-emission scanning electron microscopy along with energy-dispersive spectroscopy and X-ray diffractometry. The resulting nanostructured samples were used for electrochemical determination of the H2O2 content in a 0.1 M NaOH buffer solution using cyclic voltammetry, differential pulse voltammetry, and i–t measurements. A good linear relationship between the peak current and the concentration of H2O2 in the range from 10 to 1800 μM was obtained. The sensitivity of the obtained CuO electrode is 439.19 μA·mM−1. The calculated limit of detection is 1.34 μM, assuming a signal-to-noise ratio of 3. The investigation of the system for sensitivity to interference showed that the most common interfering substances, that is, ascorbic acid, uric acid, dopamine, NaCl, glucose, and acetaminophen, do not affect the electrochemical response. The real milk sample test showed a high recovery rate (more than 95%). According to the obtained results, this sensor is suitable for practical use for the qualitative detection of H2O2 in real samples, as well as for the quantitative determination of its concentration.

One-step synthesis of nanosilver embedding laser-induced graphene for H2O2 sensor

“…Generally, the detection potential of hydrogen peroxide is higher, and platinum electrode is used as the counter electrode [23] . However, platinum electrodes are expensive and usually used in laboratories.…”

Co3O4 Nanostructured Sensor for Electrochemical Detection of H2O2 as a Stress Biomarker in Barley: Fe3O4 Nanoparticles-Mediated Enhancement of Salt Stress Tolerance

“…The necessity of a supporting electrolyte with a high pH for an effective electrocatalytic process has been previously established in our earlier publication [ 82 ]. This phenomenon is elucidated by the presence of hydroxide ions generated through oxyhydroxide formation, which is essential for facilitating the diffusion process within the nanostructured layer.…”

“…To study the operating features of the sensor, measurements were carried out according to the scheme described in detail in our previous publication [ 82 ]. The detection process is shown schematically in Figure 1 .…”

Electrochemical sensors for the safety and quality control of cosmetics: An overview of achievements and challenges

“…Here we refine the search and present exclusively the electrochemical sensors applicable in the H2O2 analysis of cosmetics, medical and cleaning products. Copper oxide/graphitic carbon nitride composite (CuO/g-C3N4) dropped onto GCE [34], nanosized bismuth particles modified electrode (SPAgE-Bi nano ) [35], carbon paste electrode modified with nano-composite of reduced graphene oxide and CuFe2O4 nanoparticles (RGO/CuFe2O4/CPE) [36], CuO/Cu wire [37], 3D printed graphene electrode with Prussian blue (3DGrE/PB) (Figure 3) [38], as well as carbon electrodes modified with perovskites-type oxides [39][40][41][42] were developed, characterized and successfully used as working electrodes for the electrochemical detection of H2O2 in a wide range of cosmetics and antiseptic products (Table 1).…”