This paper studies the free vibration of polymer nanocomposite reinforced by graphene sheet. In this work, the new size dependent formulation is presented for nanocomposites based on couple stress theory. For this purpose, the first shear deformation theory is applied. The effect of scale parameter is investigated based on anisotropic couple stress theory. Vibration equations of the composite lamina are extracted using Hamilton’s principle. Numerical results are provided for Poly methyl methacrylate/graphene composite.Mechanical properties of the composite are obtained from molecular dynamics simulation. Based on eigenvalue procedure, an analytical solution is obtained for the natural frequency of composite lamina. In the results section, the effect of dimensional and physical parameters are investigated on lamina natural frequency. It is observed that graphene defects caused to diminish the lamina frequency. Furthermore, it is revealed that the increase in graphene volume fraction leads to natural frequency be greater.