1997
DOI: 10.1016/s0048-9697(97)00166-6
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A note on the development and use of pesticides

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Cited by 10 publications
(4 citation statements)
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“…In Canada, both products are evaluated for efficacy, toxicology in animals and environmental risk 35. Both undergo non‐clinical safety investigations such as repeated dose toxicity, genotoxicity, carcinogenicity and also reproductive and developmental toxicity 36. Acute, subchronic and chronic tests are conducted to explore the potential for adverse reactions, and results are extrapolated for their significance to children, to the elderly and to pregnant and lactating women.…”
Section: The Regulation Of Pharmaceuticals and Pesticides Is Similarmentioning
confidence: 99%
“…In Canada, both products are evaluated for efficacy, toxicology in animals and environmental risk 35. Both undergo non‐clinical safety investigations such as repeated dose toxicity, genotoxicity, carcinogenicity and also reproductive and developmental toxicity 36. Acute, subchronic and chronic tests are conducted to explore the potential for adverse reactions, and results are extrapolated for their significance to children, to the elderly and to pregnant and lactating women.…”
Section: The Regulation Of Pharmaceuticals and Pesticides Is Similarmentioning
confidence: 99%
“…This relationship is highly delicate for farmers, whose livelihoods solely depends upon agriculture. The application of synthetic pesticides in agriculture is a hot topic of discussion and debate because of its bidirectional effects (i) negative effects on human, environmental and ecosystem health (Uri, 1997;Wilson and Tisdell, 2001;Pethig, 2004;Pimentel, 2005;Sexton et al, 2007;Atreya, 2008a; and (ii) positive effects on humankind (Cooper and Dobson, 2007;Aktar et al, 2009). Use of synthetic pesticides in agriculture results in short-term (acute) and long-term (chronic) health problems.…”
Section: Introductionmentioning
confidence: 99%
“…They are widely used in agriculture and can contaminate rivers and other water bodies due to transport from cultivated areas [2][3][4][5]. Although the pesticide industry has developed new compounds that are more effective, even at lower concentrations, and that present lower environmental impacts [6], the misuse of such pesticides can pose considerable toxicity risks to operators, consumers, and the wider environment [7].…”
Section: Introductionmentioning
confidence: 99%