Asymptotic approximations of the Apostol-tangent numbers and polynomials were established for non-zero complex values of the parameter λ. Fourier expansion of the Apostol-tangent polynomials was used to obtain the asymptotic approximations. The asymptotic formulas for the cases λ=1 and λ=−1 were explicitly considered to obtain asymptotic approximations of the corresponding tangent numbers and polynomials.