A novel AIE-active imidazolium macrocyclic ratiometric fluorescence sensor for pyrophosphate anion

Xiong, Jia-Bin; Ban, Ding-Ding; Zhou, Yong-Juan; Li, Jin-Zhan; Chen, Siru; Liu, Guoqun; Tian, Jingjing; Mi, Liwei; Li, Dong‐Mi

doi:10.1039/d2ra00293k

Cited by 13 publications

(8 citation statements)

References 60 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Molecular structures of all the newly synthesized compounds 6(a-d) and 7(a-d) were confirmed by 1 H NMR, 13 C NMR, and mass spectrometry (Figure S1-S24). The 1 H NMR was recorded in CDCl 3 as solvent on 500 MHz instrument.…”

Section: Characterization Aspectsmentioning

confidence: 87%

“…New triazole based silanes 7(a-d) have been synthesized and well characterized by 1 H and 13 C NMR spectroscopy along with mass spectrometry. The synthesized compound (7 a) was found ChemistrySelect to be a potent chemosensor for the detection of dihydrogen phosphate anion.…”

Section: Discussionmentioning

confidence: 99%

“…Supporting Information contains 1 H NMR, 13 C NMR, Mass spectra of compounds 6(a-d) and 7(a-d), 1 H NMR spectra of (7 aÀ H 2 PO 4 À ) complex and characterization data of compounds 6(a-d) and 7(a-d).…”

Section: Computational Detailsmentioning

confidence: 99%

“…[8][9][10] Abnormal levels of phosphorus can be a cause of arthritis [11] and Monckeberg's arteriosclerosis. [12,13] Hence phosphate form an integral part of agriculture industry, fertilizers, food additives and medicine. [14][15][16][17][18] However, if present in excess the phosphates can cause other health issues like abnormal renal function and can impact ecological balance.…”

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Click‐Generated Triazole‐Based Silanes: A Potent Chemosensor for Dihydrogen Phosphate

et al. 2023

View full text Add to dashboard Cite

Over the years, ground and surface water has been reported to be contaminated with phosphates. These phosphates are known to cause various diseases and if present in excess can lead to eutrophication. The known silane chemistry has not been thoroughly investigated for the sensing of anions. In the current study four new triazole based silanes have been prepared by the renowned Click Chemistry for the selective and sensitive detection of dihydrogen phosphate. The synthesized compounds were well characterized by various spectroscopic techniques and their absorptive and emissive responses were investigated for the recognition of dihydrogen phosphate ions. The binding ratio between triazole based silane chemosensor and dihydrogen phosphate has been discovered from Job's plot and was also confirmed by non‐linear fitting method. The value of association constant was found to be 571.18 M−1. The limit of detection (LOD) and limit of quantitation (LOQ) were calculated by fluorescence spectroscopy. The results obtained clearly illustrated that triazole based silane could be used as a potent chemosensor for selective and sensitive recognition of dihydrogen phosphate. Further, the possible binding site of chemosensor for dihydrogen phosphate has been identified from 1H NMR studies and DFT calculations. At last real sample analysis was performed to check the practical applicability of chemosensor.

show abstract

Section: Characterization Aspectsmentioning

confidence: 87%

Section: Discussionmentioning

confidence: 99%

Section: Computational Detailsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Click‐Generated Triazole‐Based Silanes: A Potent Chemosensor for Dihydrogen Phosphate

et al. 2023

View full text Add to dashboard Cite

show abstract

“…In short, ratiometric fluorescence sensors have received increasing research attention due to their simple operation, safety, good stability, and suitability for high-throughput screening applications [ 26 ]. In the past few years, the ratiometric fluorescent sensors have been extensively used in the detection of diverse analytes including metal ions [ 27 , 28 , 29 ], anions [ 30 , 31 ], organic pollutants [ 32 ], and biomacromolecules [ 33 ]. However, a smartphone-based ratiometric fluorescent sensor for the detection of Ca 2+ content in bovine serum, to the best of our knowledge, has not been developed.…”

Section: Introductionmentioning

confidence: 99%

A Portable Smartphone-Based System for the Detection of Blood Calcium Using Ratiometric Fluorescent Probes

Zhang

et al. 2022

Biosensors

View full text Add to dashboard Cite

Hypocalcemia is a disease that adversely affects the production and reproduction of dairy cows. A portable device for rapid bovine blood calcium sensing has been growing in demand. Herein, we report a smartphone-based ratiometric fluorescence probe (SRFP) platform as a new way to detect and quantify calcium ions (Ca2+) in blood serum. Specifically, we employed a cost-effective and portable smartphone-based platform coupled with customized software that evaluates the response of Ca2+ ions to ratiometric fluorescence probe in bovine serum. The platform consists of a three-dimensional (3D) printed housing and low-cost optical components that excite fluorescent probe and selectively transmit fluorescence emissions to smartphones. The customized software is equipped with a calibration model to quantify the acquired fluorescence images and quantify the concentration of Ca2+ ions. The ratio of the green channel to the red channel bears a highly reproducible relationship with Ca2+ ions concentration from 10 μM to 40 μM in bovine serum. Our detection system has a limit of detection (LOD) of 1.8 μM in bovine serum samples and the recoveries of real samples ranged from 92.8% to 110.1%, with relative standard deviation (RSD) ranging from 1.72% to 4.89%. The low-cost SRFP platform has the potential to enable campesino to rapidly detect Ca2+ ions content in bovine serum on-demand in any environmental setting.

show abstract

The Designs and Applications of Tetraphenylethylene Macrocycles and Cages

Li,

Zuo,

Wang

et al. 2024

Chemistry A European J

View full text Add to dashboard Cite

Macrocycles and cages are very attractive for the development of functional materials due to their unique inner cavities. Building blocks with interesting functions and synthetic conveniences are especially attractive. Tetraphenylethylene (TPE) is such an entity with C2 symmetry and tetrakis‐functional groups easily modifiable. As a typical aggregation‐induced emission (AIE) active compound, TPE perfectly unites the functions of fluorescence and structural building blocks together. The unique marriage of the two roles into one component makes TPE an ideal platform for the development of functional molecular systems including macrocycles and cages. The TPE macrocycles and cages are not merely a simple combination of those two but also generate added values unseen in either component alone. The fluorescence properties of TPE in macrocycles/cages are greatly improved or modulated, which makes them more suitable for various applications compared to their linear counterparts. In this review, the chemistry and design principles of TPE macrocycles/cages are surveyed first. The unique properties of those compounds are also discussed to provide general guidance for their functionalization. A brief discussion of their applications focusing on the utilization of their unique fluorescence is also presented. In the last, outlooks and future perspectives of TPE macrocycles/cages are provided for further developments.

show abstract

A novel AIE-active imidazolium macrocyclic ratiometric fluorescence sensor for pyrophosphate anion

Abstract: The fluorescence of an imidazolium macrocycle can be switched from monomer emission to aggregate emission in the presence of pyrophosphate anion and zinc ion, which can be used as a ratiometric fluorescence sensor for pyrophosphate anion in water.

Cited by 13 publications

References 60 publications

Click‐Generated Triazole‐Based Silanes: A Potent Chemosensor for Dihydrogen Phosphate

Click‐Generated Triazole‐Based Silanes: A Potent Chemosensor for Dihydrogen Phosphate

A Portable Smartphone-Based System for the Detection of Blood Calcium Using Ratiometric Fluorescent Probes

The Designs and Applications of Tetraphenylethylene Macrocycles and Cages

Contact Info

Product

Resources

About