A novel and cost effective isatin based Schiff base fluorophore: a highly efficient “turn-off” fluorescence sensor for the selective detection of cysteine in an aqueous medium

Abstract

A novel schiff base ligand 3-(2-Amino-4, 5-dimethyl-phenylimino)-5-phenyl-1, 3-dihydro-indol-2-one (MPD 5MI) and was characterized using spectroscopic methods including UV visible, Infrared, 1H-NMR, 13C-NMR and mass spectrometry. The essential fluorescence properties such...

A novel Salen-based dual channel sensor for easy and selective nanomolar detection of l-cysteine

“…In the case of ref. 64, the sensor is a relatively simple isatin-based sensor which offers a high level of detection limit (10 −11 M) but the sensor is a fluorescence-based one and it lacks the purity that the single crystal structure offers. However in another work, 65 a copper-based sensor is used for immediate sensing of l -Cyst at the micromolar level, but the crystalline form of the sensor is not yet established.…”

In vitro Antioxidant Activities of Some Re(I) Metal Carbonyls Synthesized from Isatin Derivatives

“…8 More importantly, N-alkylated isatin Schiff base complexes are used in fluorescence microscopy as a highly efficient 'turn-off' fluorescence sensor and they have received much attention recently. 9 Although the synthesis of rhenium tri-and dicarbonyl complexes suitable for diagnostic and therapeutic antitumor applications 10 is fast gaining more attention, there is little or no literature on such bioactive compounds consisting of isatin Schiff bases coordinating to the rhenium metal through oxygen and nitrogen donor atoms. This research was geared towards that.…”