A novel and efficient magnetic nanocatalyst functionalized with 1,3,5-tris(2-hydroxyethyl)isocyanurate and boric acid for the synthesis of symmetric and asymmetric Hantzsch esters

Abstract

An efficient synthesis of polyhydroquinolines (PHQs) and polyhydroacridines (PHAs) via onepot multicomponent reactions of ꞵ-dicarbonyl, different aldehydes, and ammonium acetate catalyzed by a novel nano-catalyst Fe3O4/SiO2 functionalized with Boric Acid in EtOH under reflux conditions. It has excellent yield with straightforward workup. The catalyst which been used in this process is a mild heterogeneous catalyst that is environmentally friendly, renewable and recoverable that reused six times without significant loss of its activity.