It is well-acknowledged that the northern margin of the Gondwana supercontinent was affected by a major magmatic event at late Cambrian (Furongian) to early Ordovician (Tremadocian) times. However, an accurate assessment of its extent, origin, and significance is partly hampered by the incomplete characterization of the numerous gneiss massifs exposed in the inner part of the Variscan belt, as some of them possibly represent dismembered and deformed Furongian–Tremadocian igneous bodies. In this study, we document the case of the “Cézarenque–Joyeuse” gneisses in the Cévennes parautochton domain of the French Massif Central. The gneisses form decametre- to kilometre-thick concordant massifs interlayered within a pluri-kilometric sequence of mica- and quartz schists. They encompass two main petrological types: augen gneisses and albite gneisses, both typified by their blue and engulfed quartz grains with the augen facies differing by the presence of centimetre-sized pseudomorphs after K-feldspar and the local preservation of igneous textures. Whole-rock geochemistry highlights that many gneisses have magmatic ferrosilicic (acidic with anomalously high FeOt and low CaO) compositions while others are akin to grauwackes. Collectively, it is inferred that the bulk of the Cézarenque–Joyeuse gneisses represent former rhyodacite lava flows or ignimbrites and associated epiclastic tuffs. Volumetrically subordinate, finer-grained, and strongly silicic leucogneisses are interpreted as microgranite dykes originally intrusive within the volcanic edifices. LA–ICP–MS U–Pb dating of magmatic zircon grains extracted from an augen gneiss and a leucogneiss brackets the crystallization age of the silicic magmas between 486.1±5.5 Ma and 483.0±5.5 Ma which unambiguously ties the Cézarenque–Joyeuse gneisses to the Furongian–Tremadocian volcanic belt of SW Europe. Inherited zircon date distributions, Ti-in-zircon and zircon saturation thermometry demonstrate that they formed by melting at 750–820 °C of Ediacaran sediments. Zircon Eu/Eu* and Ce/Ce* systematics indicate that the melts were strongly reduced (fO2 probably close to the values expected for the iron–wustite buffer), possibly because they interacted during ascent with Lower Cambrian black shales. This would have enhanced Fe solubility in the melt phase and may explain the peculiar ferrosilicic signature displayed by many Furongian–Tremadocian igneous rocks in the northern Gondwana realm. We infer that crustal melting resulted from a combination of mantle-derived magma underplating in an extensional environment and anomalously elevated radiogenic heat production within the Ediacaran sedimentary sequences.