A novel aptamer- metal ions- nanoscale MOF based electrochemical biocodes for multiple antibiotics detection and signal amplification

Chen, Meng; Gan, Ning; Zhou, You; Li, Tianhua; Xu, Qing; Cao, Yuting; Chen, Yinji

doi:10.1016/j.snb.2016.08.185

Cited by 143 publications

(58 citation statements)

References 44 publications

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“…Like the other antibiotics, there are more reports of constructed electrochemical aptasensors for the detection of chloramphenicol [ 41 , 49 , 112 , 164 , 165 , 166 , 167 , 168 , 169 , 170 , 171 , 172 , 173 , 174 , 175 ] As shown in Table 9 , the lowest LOD could be obtained using the proposed electrochemical aptasensor based on Y-shaped DNA probes [ 174 ]. These probe-based metal ions encoded the nanoscale metal-organic frameworks (NMOF) as a substrate, and a circular strand-replacement DNA polymerization (CSRP) target triggered the amplification strategy.…”

Section: Aptasensors For Different Antibiotic Classesmentioning

confidence: 99%

“…Alternatively the conformational change increases the distance between the redox probe and the surface electrode, resulting in an interruption of the previous electron transfer, designated as “signal off” mode [ 25 ]. A simultaneous detection of more than one target analyte is possible by using various metal ions, e.g., Cd 2+ , Pb 2+ , Zn 2+ , and Cu 2+ , with diverse redox potentials to produce distinguishable electrochemical signals [ 49 ]. These kinds of probes are designated as metal-labelled biocodes [ 49 ].…”

Section: Introductionmentioning

confidence: 99%

“…A simultaneous detection of more than one target analyte is possible by using various metal ions, e.g., Cd 2+ , Pb 2+ , Zn 2+ , and Cu 2+ , with diverse redox potentials to produce distinguishable electrochemical signals [ 49 ]. These kinds of probes are designated as metal-labelled biocodes [ 49 ]. Usually electrochemical measurements are carried out in a conventional three-electrode system, containing a working electrode (e.g., Au or glassy carbon), a reference electrode (e.g., Ag/AgCl or saturated calomel), an auxiliary electrode (e.g., platinum wire), and a redox probe in buffer solution (e.g., [Fe(CN) 6 ] 4−/3− ).…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Aptamer-Based Biosensors for Antibiotic Detection: A Review

2018

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Antibiotic resistance and, accordingly, their pollution because of uncontrolled usage has emerged as a serious problem in recent years. Hence, there is an increased demand to develop robust, easy, and sensitive methods for rapid evaluation of antibiotics and their residues. Among different analytical methods, the aptamer-based biosensors (aptasensors) have attracted considerable attention because of good selectivity, specificity, and sensitivity. This review gives an overview about recently-developed aptasensors for antibiotic detection. The use of various aptamer assays to determine different groups of antibiotics, like β-lactams, aminoglycosides, anthracyclines, chloramphenicol, (fluoro)quinolones, lincosamide, tetracyclines, and sulfonamides are presented in this paper.

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Section: Aptasensors For Different Antibiotic Classesmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Aptamer-Based Biosensors for Antibiotic Detection: A Review

2018

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“…Particular attention is given to the type of nanostructures and their role, target analyte, electrochemical technique and reported application. Although immunosensors and DNA sensors have been mostly prepared, aptasensors and others have been developed for the determination of: food allergens [ 18 , 61 , 62 , 63 , 64 , 65 , 66 , 67 , 68 ]; gluten [ 69 , 70 ]; GMOs [ 10 , 20 , 21 , 23 ]; toxins [ 32 , 71 , 72 ]; antibiotics [ 34 , 59 , 73 , 74 ]; pesticide residues [ 57 ]; bacteria [ 19 , 26 , 36 ]; fungus [ 22 , 75 ]; and yeast [ 76 ]. The biosensors were developed either in integrated formats or by coupling MNPs to conventional or screen-printed electrode substrates.…”

Section: Selected Nanostructures In Electrochemical Biosensing Formentioning

confidence: 99%

“…The development of integrated biosensors implies the use as scaffolds of conventional (glassy carbon, GCE, and gold, AuE) or screen-printed (SPCE, SPGE) electrodes, in many cases modified with single (AuNPs, CNTs, CAs, CNFs, G, GO, GQDs) or hybrids (PAMAM(Au), AuNPs-rGO, chitosan-modified multi-walled carbon nanotubes, CS-MWCNTs) nanomaterials, as well as with diverse nanostructures of MIPs and MOFs. A limited number of biosensors uses unmodified electrode substrates and nanomaterials as nanocarriers and/or catalytic labels [ 32 , 71 , 74 ]. Some methods combine the use of different nanomaterials with different roles within the same design.…”

Section: Selected Nanostructures In Electrochemical Biosensing Formentioning

confidence: 99%

Electrochemical Affinity Biosensors Based on Selected Nanostructures for Food and Environmental Monitoring

Campuzano

Yáñez‐Sedeño

Pingarrón

2020

Sensors

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The excellent capabilities demonstrated over the last few years by electrochemical affinity biosensors should be largely attributed to their coupling with particular nanostructures including dendrimers, DNA-based nanoskeletons, molecular imprinted polymers, metal-organic frameworks, nanozymes and magnetic and mesoporous silica nanoparticles. This review article aims to give, by highlighting representative methods reported in the last 5 years, an updated and general overview of the main improvements that the use of such well-ordered nanomaterials as electrode modifiers or advanced labels confer to electrochemical affinity biosensors in terms of sensitivity, selectivity, stability, conductivity and biocompatibility focused on food and environmental applications, less covered in the literature than clinics. A wide variety of bioreceptors (antibodies, DNAs, aptamers, lectins, mast cells, DNAzymes), affinity reactions (single, sandwich, competitive and displacement) and detection strategies (label-free or label-based using mainly natural but also artificial enzymes), whose performance is substantially improved when used in conjunction with nanostructured systems, are critically discussed together with the great diversity of molecular targets that nanostructured affinity biosensors are able to quantify using quite simple protocols in a wide variety of matrices and with the sensitivity required by legislation. The large number of possibilities and the versatility of these approaches, the main challenges to face in order to achieve other pursued capabilities (development of antifouling, continuous operation, wash-, calibration- and reagents-free devices, regulatory or Association of Official Analytical Chemists, AOAC, approval) and decisive future actions to achieve the commercialization and acceptance of these devices in our daily routine are also noted at the end.

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Metal‐Organic Frameworks and Electrospinning: A Happy Marriage for Wastewater Treatment

Ahmadijokani

Molavi

Bahi

et al. 2022

Adv Funct Materials

113

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Metal-organic frameworks (MOFs), an emerging class of porous organic-inorganic hybrid materials, have shown great potential for water and wastewater treatment applications. However, pure MOF powders have limited practical applications in water treatment due to their insolubility, poor processability, brittleness, safety hazard from dust formation, and difficult separation from aqueous solutions. Thus, exploring potential MOFs composites with improved separation performance is of great importance. The marriage of MOFs with electrospun nanofiber with forethought into the final product's morphology, structure, and chemistry has opened up new opportunities for efficient wastewater treatment. The present review exhaustively summarizes the strategies to integrate MOFs into nanofibers via electrospinning to remove various pollutants (i.e., organic dyes, heavy metal ions, pharmaceuticals, personal care products, oily compounds, organic solvents, etc.) via adsorption, photodegradation, and membrane filtration. Besides, the most recent advances of electrospun MOF nanofibers for wastewater treatment and their current challenges and future outlook are delineated.

show abstract

A novel aptamer- metal ions- nanoscale MOF based electrochemical biocodes for multiple antibiotics detection and signal amplification

Cited by 143 publications

References 44 publications

Aptamer-Based Biosensors for Antibiotic Detection: A Review

Aptamer-Based Biosensors for Antibiotic Detection: A Review

Electrochemical Affinity Biosensors Based on Selected Nanostructures for Food and Environmental Monitoring

Metal‐Organic Frameworks and Electrospinning: A Happy Marriage for Wastewater Treatment

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