Carissa carandas L. (Karonda) fruits remain neglected in India, despite their effectiveness in achieving nutritional requirements. The majority of the underutilized fruits are widely accessible and native to the locality. The article intends to demonstrate the many positive health effects of Karonda fruits, which are composed of a number of anti-oxidant, bioactive and phytochemical components. Thus, the fruit has an abundance of nutrients and can help alleviate a variety of ailments. It is currently regarded as an essential source for multiple distinctive products for the production of several commercial products as well as medicines for different illnesses. The intention of this review paper is to analyse the pharmacologic and therapeutic findings that will assist in discovering the medicinal value of Karonda fruits while unlocking the way for more investigation into the detection of health effects in in vivo human studies.