A Novel Case of Diabetic Muscle Necrosis in a Patient with Cystic Fibrosis-Related Diabetes

Chalasani, Sreelatha; Bettadahalli, Shankar S.; Bhupathi, Satya V.; Aswani, Vijay

doi:10.3121/cmr.2013.1124

Cited by 3 publications

(2 citation statements)

References 16 publications

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“…Typically, patients have no fever, normal white blood cell count, normal blood sedimentation rate, but elevated C‐reactive protein . Usually, myonecrosis occurs in poorly controlled diabetes . The diagnosis is established by muscle MRI, and the treatment of choice is bed rest and analgesics .…”

Section: Resultsmentioning

confidence: 99%

Secondary myopathy due to systemic diseases

et al. 2016

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Section: Resultsmentioning

confidence: 99%

Secondary myopathy due to systemic diseases

et al. 2016

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“…Diabetes mellitus may cause diabetic myopathy [100][101][102] with a wide range of abnormalities, such as painless muscle wasting (diabetic amyotrophy), muscle inflammation, ischaemia, infarction, fibrosis, fatty atrophy, haemorrhage and diabetic myonecrosis, a self-limiting condition with acute onset of oedema and severely painful muscle necrosis. Usually, myonecrosis occurs in poorly controlled diabetes [103,104]. The development of RM in diabetic patients depends on the severity of serum hyperosmolarity and the presence of hypernatraemia [77,105].…”

Section: Diabetes Mellitusmentioning

confidence: 99%

Non-traumatic and non-drug-induced rhabdomyolysis

Kolovou

Cokkinos

Bilianou

et al. 2019

Arch Med Sci Atheroscler Dis

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Rhabdomyolysis (RM), a fortunately rare disease of the striated muscle cells, is a complication of non-traumatic (congenital (glycogen storage disease, discrete mitochondrial myopathies and various muscular dystrophies) or acquired (alcoholic myopathy, systemic diseases, arterial occlusion, viral illness or bacterial sepsis)) and traumatic conditions. Additionally, RM can occur in some individuals under specific circumstances such as toxic substance use and illicit drug abuse. Lipid-lowering drugs in particular are capable of causing RM. This comprehensive review will focus on non-traumatic and nondrug-induced RM. Moreover, the pathology of RM, its clinical manifestation and biochemical effects, and finally its management will be discussed.

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Diabetic muscle infarction: a systematic review

Horton

Taylor

Ragland

et al. 2015

BMJ Open Diab Res Care

198

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ContextDiabetic muscle infarction (DMI) is a rare complication associated with poorly controlled diabetes mellitus. Less than 200 cases have been reported in the literature since it was first described over 45 years ago. There is no clear ‘standard of care’ for managing these patients.Evidence acquisitionPubMed searches were conducted for ‘diabetic muscle infarction’ and ‘diabetic myonecrosis’ from database inception through July 2014. All articles identified by these searches were reviewed in detail if the article text was available in English.Evidence synthesisThe current literature exists as case reports or small case series, with no prospective or higher-order treatment studies available. Thus, an evidence-based approach to data synthesis was difficult. The available literature is presented objectively with an attempt to describe clinically relevant trends and findings in the diagnosis and management of DMI.ConclusionsEarly recognition of DMI is key, so appropriate treatment can be initiated. MRI is the radiological study of choice. A combination of bed rest, glycemic control, and non-steroidal anti-inflammatory drug therapy appears to yield the shortest time to symptom resolution and the lowest risk of recurrence.

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A Novel Case of Diabetic Muscle Necrosis in a Patient with Cystic Fibrosis-Related Diabetes

Cited by 3 publications

References 16 publications

Secondary myopathy due to systemic diseases

Secondary myopathy due to systemic diseases

Non-traumatic and non-drug-induced rhabdomyolysis

Diabetic muscle infarction: a systematic review

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