A novel colorimetric and ratiometric fluorescent probe for targeted detection of hypochlorous acid based on HClO-mediated anthracene-hydrazone to anthracene-triazole transformation

Abstract

An anthracene-based fluorescence probe B-ClO that exhibited excellent selectivity and sensitivity for colorimetric and ratiometric detection of ClO− in 80% aqueous DMF solution has been designed and developed.

A ratiometric small-molecule fluorescent probe for the selective detection of hypochlorite by an oxidative cyclization reaction: application to commercial disinfectants and live cells

“…[19][20][21][22] Among the most commonly used recognition moieties for hypochlorite detection, 2-hydrazino benzothiazole has a few limited applications, and there are only a few reports based on this moiety where hypochlorous-acid-activated intramolecular cyclization of heterocyclic hydrazone occurred to form a new product (1,2,4-triazole). [23][24][25] Based on our research on the oxidation reaction of hypochlorite, we constructed a new yellowemitting thiophene-based ratiometric fluorescent probe, TPBN, via the Suzuki cross-coupling reaction. Initially, the yellow fluorescence was observed due to the presence of strong ICT, and after the incorporation of hypochlorite, there was a cyclization-induced weakening of the ICT process, resulting in the weak blue-emitting 1,2,4-triazole product (TPBN-P).…”