A novel colorimetric chemosensor based on quinoline for the sequential detection of Fe3+ and PPi in aqueous solution

Colorimetric Sensing Strategy through the Coordination Chemistry between Ascorbic Acid 2-Phosphate and Copper Ions

“…Phosphate ester has gained great interest in analytical applications . As a typical bisphosphonate, pyrophosphate ion (PPi) has been widely reported to exhibit strong affinities toward metal ions, and many detection methods have been proposed based on the strong affinities between PPi and certain ions like Al 3+ , Zn 2+ , Cu 2+ , and Fe 3+ . − For instance, a turn-on fluorescent detection strategy was proposed based on the strong binding of PPi with Cu 2+ to form the PPi–Cu 2+ –PPi complex, which efficiently hindered the generation of fluorescent copper nanoparticles . Ascorbic acid 2-phosphate (AAP) is also a widely used substrate due to its hydrolyzed product ascorbic acid (AA), which exhibits great reducibility and can regulate several redox couples. − The hydrolysis of AAP into AA can be completed under the catalysis of alkaline phosphatase (ALP), which accounts for the sensing mechanism in many ALP-based sensors .…”

A Naphthalimides‐Based Probe for Sequential Detection of Cu2+ and PPi and Its Application in Cells Imaging

“…For example, PPi is considered as a potential biomarker for the diagnosis of chondrocalcinosis [13–15] . So far, more and more attention has been paid to the development of PPi chemsensors [16–17] . However, a major problem in PPi detection is the interference from other coexisting anions.…”

“…[13][14][15] So far, more and more attention has been paid to the development of PPi chemsensors. [16][17] However, a major problem in PPi detection is the interference from other coexisting anions. Therefore, it is particularly important to develop fluorescence probe with good specificity and high sensitivity for PPi detection.…”

A Deferasirox Derivative That Acts as a Multifaceted Platform for the Detection and Quantification of Fe3+

“…However, these techniques are either expensive, require costly instrumentation, or are time consuming to conduct when analyzing multiple samples. In an effort to overcome these drawbacks, researchers have focused on the development of spectrophotometric chemosensors that allow for the rapid determination of iron content in water samples using colorimetric [18][19][20][21][22][23][24][25][26][27][28] and fluorescentbased [21,23,[27][28][29][30][31][32][33][34] means. However, many of these systems require the use of organic co-solvents, such as chloroform or acetic acid.…”