A novel conductive nanocomposite-based biosensor for ultrasensitive detection of microRNA-21 in serum, using methylene blue as mediator

Carbon-based nanocomposites for biomedical applications

“…In the other studies, to address the conductivity issue of GO, conductive metal nanoparticles were introduced to reduced GO (rGO) or the nanoribbon structure of the GO and used for the detection of miRNA-21 and Human papillomavirus-16 (HPV-16) in an electrochemical manner. 55,56 In addition, to maximize the conductivity of the rGO, a nanocomposite was developed by combining rGO and molybdenum disulde (MoS 2 ) nanoparticles, a TMD nanomaterial and was used to develop an electrochemical biosensor. 57 In this study, a carbon-based nanocomposite composed of rGO and MoS 2 nanoparticles was further combined with a conductive polymer [poly (3,4-ethoxylenedioxythiophene), PEDOT] to develop an electrochemical parathyroid hormone biosensor.…”

Gold nanoparticles: promising biomaterials for osteogenic/adipogenic regulation in bone repair

“…In the medical field, they can act as regulators for cell fate, 17 wound healers, 18,19 and drug resistance antagonists. 20 Moreover, they have been developed to act as recognition probes, 21 components of biosensors, 22,23 non-antibiotic anti-microbial drugs 24 and diagnosis agents 25 for diagnostic and therapeutic purposes. Recently, some AuNP-derived materials have been demonstrated to inhibit the adipogenic differentiation of MSCs and attenuate lipid accumulation.…”